Institution
University of Konstanz
Education•Konstanz, Baden-Württemberg, Germany•
About: University of Konstanz is a education organization based out in Konstanz, Baden-Württemberg, Germany. It is known for research contribution in the topics: Population & Membrane. The organization has 12115 authors who have published 27401 publications receiving 951162 citations. The organization is also known as: University of Constance & Universität Konstanz.
Topics: Population, Membrane, Politics, Laser, Gene
Papers published on a yearly basis
Papers
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TL;DR: The results suggest that the Pe, rather than the Ne/ERN, is closely related to error detection, and specifically reflects the accumulated evidence that an error has been committed.
Abstract: The ability to detect and compensate for errors is crucial in producing effective, goal-directed behavior Human error processing is reflected in two event-related brain potential components, the error-related negativity (Ne/ERN) and error positivity (Pe), but the functional significance of both components remains unclear Our approach was to consider error detection as a decision process involving an evaluation of available evidence that an error has occurred against an internal criterion This framework distinguishes two fundamental stages of error detection—accumulating evidence (input), and reaching a decision (output)—that should be differentially affected by changes in internal criterion Predictions from this model were tested in a brightness discrimination task that required human participants to signal their errors, with incentives varied to encourage participants to adopt a high or low criterion for signaling their errors Whereas the Ne/ERN was unaffected by this manipulation, the Pe varied consistently with criterion: A higher criterion was associated with larger Pe amplitude for signaled errors, suggesting that the Pe reflects the strength of accumulated evidence Across participants, Pe amplitude was predictive of changes in behavioral criterion as estimated through signal detection theory analysis Within participants, Pe amplitude could be estimated robustly with multivariate machine learning techniques and used to predict error signaling behavior both at the level of error signaling frequencies and at the level of individual signaling responses These results suggest that the Pe, rather than the Ne/ERN, is closely related to error detection, and specifically reflects the accumulated evidence that an error has been committed
253 citations
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TL;DR: It is shown that the chaperone-associated ubiquitin ligase CHIP is able to induce the proteasomal degradation of p53, and that mutant and wild-type p53 transiently associate with molecular chaperones and can be diverted onto a degradation pathway through this association.
253 citations
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TL;DR: The ability to oxidize ferrous iron anaerobically with nitrate at approximately pH 7 appears to be a widespread capacity among mesophilic denitrifying bacteria.
Abstract: Nine out of ten anaerobic enrichment cultures inoculated with sediment samples from various freshwater, brackish-water, and marine sediments exhibited ferrous iron oxidation in mineral media with nitrate and an organic cosubstrate at pH 7.2 and 30° C. Anaerobic nitrate-dependent ferrous iron oxidation was a biological process. One strain isolated from brackish-water sediment (strain HidR2, a motile, nonsporeforming, gram-negative rod) was chosen for further investigation of ferrous iron oxidation in the presence of acetate as cosubstrate. Strain HidR2 oxidized between 0.7 and 4.9 mM ferrous iron aerobically and anaerobically at pH 7.2 and 30° C in the presence of small amounts of acetate (between 0.2 and 1.1 mM). The strain gained energy for growth from anaerobic ferrous iron oxidation with nitrate, and the ratio of iron oxidized to acetate provided was constant at limiting acetate supply. The ability to oxidize ferrous iron anaerobically with nitrate at approximately pH 7 appears to be a widespread capacity among mesophilic denitrifying bacteria. Since nitrate-dependent iron oxidation closes the iron cycle within the anoxic zone of sediments and aerobic iron oxidation enhances the reoxidation of ferrous to ferric iron in the oxic zone, both processes increase the importance of iron as a transient electron carrier in the turnover of organic matter in natural sediments.
252 citations
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TL;DR: A microscopic method was developed that uses elastic optical waveguides to visualize and measure forces locally exerted by single appressoria of C. graminicola, and found the force exerted was about 17 micronewtons.
Abstract: Many plant pathogenic fungi, such as the cereal pathogen Colletotrichum graminicola, differentiate highly specialized infection structures called appressoria, which send a penetration peg into the underlying plant cell. Appressoria have been shown to generate enormous turgor pressure, but direct evidence for mechanical infection of plants by fungi is lacking. A microscopic method was developed that uses elastic optical waveguides to visualize and measure forces locally exerted by single appressoria. By this method, the force exerted by appressoria of C. graminicola was found to be about 17 micronewtons.
252 citations
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University of Konstanz1, University of Zurich2, Australian National University3, Southern Illinois University Carbondale4, Pompeu Fabra University5, University of Cambridge6, German Primate Center7, Durham University8, Andrews University9, Liverpool John Moores University10, University of Amsterdam11, University of Southern California12, University of Portsmouth13, Wellcome Trust Sanger Institute14, Biomedical Primate Research Centre15, Murdoch University16, University of Bern17, Bogor Agricultural University18, Sabah Wildlife Department19, Cardiff University20, Zurich University of Applied Sciences/ZHAW21, Swiss Institute of Bioinformatics22, Catalan Institution for Research and Advanced Studies23
TL;DR: It is shown that an isolated population from Batang Toru, at the southernmost range limit of extantSumatran orangutans south of Lake Toba, is distinct from other northern Sumatran and Bornean populations, and a new species, Pongo tapanuliensis, is identified.
252 citations
Authors
Showing all 12272 results
Name | H-index | Papers | Citations |
---|---|---|---|
Robert E. W. Hancock | 152 | 775 | 88481 |
Lloyd J. Old | 152 | 775 | 101377 |
Andrew White | 149 | 1494 | 113874 |
Stefanie Dimmeler | 147 | 574 | 81658 |
Rudolf Amann | 143 | 459 | 85525 |
Niels Birbaumer | 142 | 835 | 77853 |
Thomas P. Russell | 141 | 1012 | 80055 |
Emmanuelle Perez | 138 | 1550 | 99016 |
Shlomo Havlin | 131 | 1013 | 83347 |
Bruno S. Frey | 119 | 900 | 65368 |
Roald Hoffmann | 116 | 870 | 59470 |
Michael G. Fehlings | 116 | 1189 | 57003 |
Yves Van de Peer | 115 | 494 | 61479 |
Axel Meyer | 112 | 511 | 51195 |
Manuela Campanelli | 111 | 675 | 48563 |