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Institution

University of Lisbon

EducationLisbon, Lisboa, Portugal
About: University of Lisbon is a education organization based out in Lisbon, Lisboa, Portugal. It is known for research contribution in the topics: Population & Context (language use). The organization has 19122 authors who have published 48503 publications receiving 1102623 citations. The organization is also known as: Universidade de Lisboa & Lisbon University.


Papers
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Journal ArticleDOI
TL;DR: The cumulative consequences of VPA therapy in inborn errors of metabolism (IEMs) and the importance of recognizing an underlying IEM in cases of Vpa-induced steatosis and acute liver toxicity are two different concepts that will be emphasized.
Abstract: Valproic acid (VPA; 2-n-propylpentanoic acid) is widely used as a major drug in the treatment of epilepsy and in the control of several types of seizures. Being a simple fatty acid, VPA is a substrate for the fatty acid β-oxidation (FAO) pathway, which takes place primarily in mitochondria. The toxicity of valproate has long been considered to be due primarily to its interference with mitochondrial β-oxidation. The metabolism of the drug, its effects on enzymes of FAO and their cofactors such as CoA and/or carnitine will be reviewed. The cumulative consequences of VPA therapy in inborn errors of metabolism (IEMs) and the importance of recognizing an underlying IEM in cases of VPA-induced steatosis and acute liver toxicity are two different concepts that will be emphasized.

330 citations

Journal ArticleDOI
Morad Aaboud, Alexander Kupco1, Peter Davison2, Samuel Webb3  +2944 moreInstitutions (220)
TL;DR: In this article, a search for new resonant and non-resonant high-mass phenomena in dielectron and dimuon fi nal states was conducted using 36 : 1 fb(-1) of proton-proton collision data.
Abstract: A search is conducted for new resonant and non-resonant high-mass phenomena in dielectron and dimuon fi nal states. The search uses 36 : 1 fb(-1) of proton-proton collision data, collected at root ...

329 citations

Journal ArticleDOI
TL;DR: An improved method to determine the degree of acetylation of chitins and chitosans was outlined and can easily be extended to the other polymorphic forms and to other ranges of DA values.

329 citations

Journal ArticleDOI
TL;DR: The chemical composition, antioxidant and antibacterial activities of essential oils isolated by hydrodistillation from the aerial parts of Tunisian Thymus capitatus Hoff as discussed by the authors during the different phases of the plant development, and from different locations, were evaluated.

328 citations

Journal ArticleDOI
TL;DR: In this article, a 57-year hindcast (1953-2009) obtained with a spectral wave model forced with reanalysis wind fields was used to investigate the variability in the North-East Atlantic Ocean (25°W-0°W and 30°N-60° N).

328 citations


Authors

Showing all 19716 results

NameH-indexPapersCitations
Joao Seixas1531538115070
A. Gomes1501862113951
Marco Costa1461458105096
António Amorim136147796519
Osamu Jinnouchi13588586104
P. Verdier133111183862
Andy Haas132109687742
Wendy Taylor131125289457
Steve McMahon13087878763
Timothy Andeen129106977593
Heather Gray12996680970
Filipe Veloso12888775496
Nuno Filipe Castro12896076945
Oliver Stelzer-Chilton128114179154
Isabel Marian Trigger12897477594
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023247
2022828
20214,521
20204,517
20193,810
20183,617