University of Tsukuba

About: University of Tsukuba is a education organization based out in Tsukuba, Ibaraki, Japan. It is known for research contribution in the topics: Population & Gene. The organization has 36352 authors who have published 79483 publications receiving 1934752 citations. The organization is also known as: Tsukuba daigaku & Tsukuba University.

Control over differentiation of a metastable supramolecular assembly in one and two dimensions.

Abstract: Molecular self-assembly under kinetic control is expected to yield nanostructures that are inaccessible through the spontaneous thermodynamic process. Moreover, time-dependent evolution, which is reminiscent of biomolecular systems, may occur under such out-of-equilibrium conditions, allowing the synthesis of supramolecular assemblies with enhanced complexities. Here we report on the capacity of a metastable porphyrin supramolecular assembly to differentiate into nanofibre and nanosheet structures. Mechanistic studies of the relationship between the molecular design and pathway complexity in the self-assembly unveiled the energy landscape that governs the unique kinetic behaviour. Based on this understanding, we could control the differentiation phenomena and achieve both one- and two-dimensional living supramolecular polymerization using an identical monomer. Furthermore, we found that the obtained nanostructures are electronically distinct, which illustrates the pathway-dependent material properties.

2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.

Abstract: Ventricular arrhythmias are an important cause of morbidity and mortality and come in a variety of forms, from single premature ventricular complexes to sustained ventricular tachycardia and fibrillation. Rapid developments have taken place over the past decade in our understanding of these arrhythmias and in our ability to diagnose and treat them. The field of catheter ablation has progressed with the development of new methods and tools, and with the publication of large clinical trials. Therefore, global cardiac electrophysiology professional societies undertook to outline recommendations and best practices for these procedures in a document that will update and replace the 2009 EHRA/HRS Expert Consensus on Catheter Ablation of Ventricular Arrhythmias. An expert writing group, after reviewing and discussing the literature, including a systematic review and meta-analysis published in conjunction with this document, and drawing on their own experience, drafted and voted on recommendations and summarized current knowledge and practice in the field. Each recommendation is presented in knowledge byte format and is accompanied by supportive text and references. Further sections provide a practical synopsis of the various techniques and of the specific ventricular arrhythmia sites and substrates encountered in the electrophysiology lab. The purpose of this document is to help electrophysiologists around the world to appropriately select patients for catheter ablation, to perform procedures in a safe and efficacious manner, and to provide follow-up and adjunctive care in order to obtain the best possible outcomes for patients with ventricular arrhythmias.

Vector autoregression and causality: a theoretical overview and simulation study

Abstract: This paper provides a theoretical overview of Wald tests for Granger causality in levels vector autoregressions (VAR's) and Johansen-type error correction models (ECM's). The theory is based on results in Toda and Phillips (1991a) and allows for stochastic and deterministic trends as well as arbitrary degrees of cointegration. We recommend some operational procedures for conducting Granger causality tests that are based on the Gaussian maximum likelihood estimation of ECM's. These procedures are applicable in the important practical case of testing the causal effects of one variable on another group of variables and vice versa. This paper also investigates the sampling properties of these testing procedures through simulation exercises. Three sequential causality tests in ECM's are compared with conventional causality tests in levels and differences VAR's.

Perpendicular Magnetic Anisotropy Caused by Interfacial Hybridization via Enhanced Orbital Moment in Co / Pt Multilayers: Magnetic Circular X-Ray Dichroism Study

Abstract: Magnetic circular x-ray dichroism (MCXD) measurements at the Co ${L}_{2,3}$ and ${M}_{2,3}$ core edges reveal a strongly enhanced perpendicular Co orbital moment ( ${m}_{\mathrm{orb}}$) in Co/Pt multilayers which show perpendicular magnetic anisotropy (PMA). MCXD signals at the Pt ${N}_{6,7}$ and ${O}_{2,3}$ edges, arising from Pt $5d\ensuremath{-}\mathrm{Co}3d$ hybridization, persist for the thinnest Co layer. The hybridization is shown to be localized at the Co/Pt interface and to cause the ${m}_{\mathrm{orb}}$ enhancement which drives PMA. Unambiguous evidence for a transition from fcc to hcp Co is presented and ${m}_{\mathrm{orb}}$ of bulk fcc Co has been determined to be $0.11{\ensuremath{\mu}}_{B}$ for the first time.