Vignan University

About: Vignan University is a education organization based out in Guntur, Andhra Pradesh, India. It is known for research contribution in the topics: Computer science & Control theory. The organization has 1138 authors who have published 1381 publications receiving 7798 citations.

Bi-Directional Self-Organization Technique for Enhancing the Genetic Algorithm

Abstract: Genetic Algorithm (GA) is well-known optimization algorithm for solving various kinds of the optimization problem. GA is based on evolutionary principles and effectively solves the large-scale problem. In addition, it incorporates the variety of hybrid techniques to achieve the best performance in complex problems. However, self-organization is one of the popular model, which acquire global order from the local interaction among the individuals. The combined version of self-organization and genetic algorithm are adopted to improve the performance in attaining the convergence. This paper proposes a bi-directional self-organization process for improving the genetic algorithm which achieves the convergence and well-balanced diversity in the population. The experimentation is conducted on the standard test-bed of travelling salesman problem and instances are obtained from TSPLIB. Thus, the proposed algorithm has shown its dominance with the existing classical GA in terms of various parameter metrics.

Purification and characterization of bioactive compounds extracted from Suaeda maritima leaf and its impact on pathogenicity of Pseudomonas aeruginosa in Catla catla fingerlings

Abstract: Incidence of various dreadful microbial infections and the development of antibiotic resistance by infection causative microbes are the main reasons for reducing aquaculture productivity. Hence, there is an immense need for the discovery of alternative and efficient treatment for quick recovery of diseased fishes. In the present study, Suaeda maritima leaf extracts (hexane, diethyl ether, ethanol, and water) were screened for in vitro and in vivo antibacterial and antioxidant activities. Out of all the four extracts, ethanolic extract showed highest antibacterial activity against S. aureus (4.9 ± 1.3 mm), B. subtilis (1.6 ± 0.3 mm), K. pneumoniae (4.2 ± 1.8 mm), and P. aeruginosa (4.1 ± 1.2 mm). Similarly, antioxidant activity was also higher for ethanolic extract (500 µg/mL) based on DPPH radical scavenging ability (71.6 ± 1.4%) and reducing potential (149 μg/mL) assays. Further, ethanolic extract was purified consecutively via column chromatography and preparative TLC where an active fraction was selected based on highest antibacterial (10.1 ± 1.4 mm) and antioxidant properties (82.3 ± 2.8%). Active fraction was loaded onto mass spectroscopy and identified the presence of four active constituents such as 1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-3-yl) methanol; 3',7-Dimethoxy-3-hydroxyflavone; Saponin and (19R)9acetyl19hydroxy10,14dimethyl20oxopentacyclo[11.8.0.0 .0 .0 ]henicos-17-yl-acetate. Besides, in vivo studies were conducted on Catla catla fingerlings infected with P. aeruginosa under laboratory conditions. The fingerlings were segregated into 5 groups, among which group 4 and 5 were treated with crude and purified extracts. Both the extracts were efficient in treating infected fingerlings and recorded 100% survival rate which is even better than group-3 treated with a synthetic antibiotic (77%). Hence, S. maritima leaf extract can be considered as a possible alternative medicine in aquaculture.

Performance Analysis of 5G Waveform - Pruned DFT Spread FBMC with Real Time Fading Conditions

Abstract: The requirements of 5G wireless communication systems are low PAPR (Peak to Average Power Ratio), low latency, high throughput, low computational complexity and high spectral efficiency. All these requirements are not satisfied with one technique because in 5G there is a tradeoff between these requirements. OFDM has the drawbacks of high Peak to Average Power Ratio (PAPR), less spectral efficiency and SC-FDMA is having an advantage of Low PAPR and having all the drawbacks of OFDM. To overcome all these drawbacks, an innovative modulation technique namely Pruned DFT incorporate with one tap scaling has been suggested by Ronald Nissel et.al by combining the advantages of FBMC-OQAM and SC-FDMA. This method is having an advantage of Low PAPR similar to SC-FDMA, Low Latency, High Throughput, and Lower OOB emissions. 5G applications like Robotic surgeries, Driverless cars, Giga bits per second etc require these advantages. In this paper, Pruned DFT Spread FBMC (PDFTSFBMC) system has been simulated and tested against 3GPP defined fading profiles of EPA (Extended Pedestrian A), EVA (Extended Vehicular A), and ETU (Extended Typical Urban), which is a necessary component for a mobile communication system. From the results it has been observed that the proposed 5G FBMC system is suitable for Ultra reliable and low latency applications where low PAPR, lower bit error rate (BER), high throughput are the key requirements for 5G communications.

Synthesis, Characterization & Antimicrobial Activities of New IsoxazoleSubstituted Mannich and Schiff Bases of 5-Nitroisatin Analogs

Abstract: A sequence of new isoxazole substituted Schiff base and Mannich base of 5-nitroisatin are synthesized by a multi-step synthesis from 5-nitroisatin. Whole synthesized analogs were characterized using IR, NMR, Mass spectroscopy and microanalyses. All the Schiff and Mannich bases were tested for their antimicrobial potencies against some human pathogenic microorganism using agar well diffusion technique. The relationship between the biological activity and the functional group variation of the Schiff and Mannich bases were analyzed. Standard ciprofloxacin and ketoconazole were used to compare the antimicrobial activities of novel isatin coupled isoxazole derivatives.