Institution
Wuhan University
Education•Wuhan, China•
About: Wuhan University is a education organization based out in Wuhan, China. It is known for research contribution in the topics: Computer science & Population. The organization has 92849 authors who have published 92882 publications receiving 1691049 citations. The organization is also known as: WHU & Wuhan College.
Topics: Computer science, Population, Catalysis, Feature extraction, Apoptosis
Papers published on a yearly basis
Papers
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TL;DR: Current techniques that can be used to prepare bioactive electrospun scaffolds, including physical adsorption, blend electrospinning, coaxial electrosp spinning, and covalent immobilization are reviewed.
Abstract: A biomaterial scaffold is one of the key factors for successful tissue engineering. In recent years, an increasing tendency has been observed toward the combination of scaffolds and biomolecules, e.g. growth factors and therapeutic genes, to achieve bioactive scaffolds, which not only provide physical support but also express biological signals to modulate tissue regeneration. Huge efforts have been made on the exploration of strategies to prepare bioactive scaffolds. Within the past five years, electrospun scaffolds have gained an exponentially increasing popularity in this area because of their ultrathin fiber diameter and large surface-volume ratio, which is favored for biomolecule delivery. This paper reviews current techniques that can be used to prepare bioactive electrospun scaffolds, including physical adsorption, blend electrospinning, coaxial electrospinning, and covalent immobilization. In addition, this paper also analyzes the existing challenges (i.e., protein instability, low gene transfection efficiency, and difficulties in accurate kinetics prediction) to achieve biomolecule release from electrospun scaffolds, which necessitate further research to fully exploit the biomedical applications of these bioactive scaffolds.
370 citations
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TL;DR: The aim of this study was to investigate the changes of liver function and its clinical significance in COVID‐19 patients.
Abstract: Background The SARS-CoV-2 pandemic is an ongoing global health emergency. The aim of our study was to investigate the changes of liver function and its clinical significance in COVID-19 patients. Method This retrospective, single-centre study was conducted on 115 confirmed cases of COVID-19 in Zhongnan hospital of Wuhan University from 18 January 2020 to 22 February 2020. Liver function and related indexes were analysed to evaluate its relationship with disease progression in COVID-19 patients. Results Part of the COVID-19 patients presented with varying degrees of abnormality in liver function indexes. However, the levels of ALT, AST, TBIL, GGT and LDH in COVID-19 patients were not significantly different when compared with hospitalised community-acquired pneumonia patients, and the levels of albumin is even significantly higher. The levels of ALT, AST, TBIL, LDH and INR showed statistically significant elevation in severe COVID-19 cases compared with that in mild cases. However, the clinical significance of the elevation is unremarkable. Majority of severe COVID-19 patients showed significantly decreasing in albumin level and continuously decreasing in the progress of illness. Most of the liver function indexes in COVID-19 patients were correlated with CRP and NLR, the markers of inflammation. Logistic regression analysis further identified NLR as the independent risk factor for severe COVID-19, as well as age. Conclusions Although abnormalities of liver function indexes are common in COVID-19 patients, the impairment of liver function is not a prominent feature of COVID-19, and also may not have serious clinical consequences.
370 citations
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TL;DR: In this article, the adsorption of congo red onto the novel m-Cell/Fe 3 O 4 /ACCs was studied as a function of contact time, initial concentration of congon red, adsorbent dosage, and pH of solution.
370 citations
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TL;DR: The feasibility and prospects of the novel photochemical methods of using Fe(III) salts and oxides in wastewater treatments are being discussed in this paper.
370 citations
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Hebrew University of Jerusalem1, University of Queensland2, University of Potsdam3, Leibniz Association4, Sun Yat-sen University5, Spanish National Research Council6, Complutense University of Madrid7, University of Exeter8, Universities Space Research Association9, Wuhan University10, University of Haifa11, Marshall Space Flight Center12, Cooperative Institute for Research in the Atmosphere13, University of Maryland, College Park14, Goddard Space Flight Center15, National Oceanic and Atmospheric Administration16, Colorado School of Mines17
TL;DR: In this article, the authors outline the historical development of night-time optical sensors up to the current state-of-the-art sensors, highlight various applications of night light data, discuss the special challenges associated with remote sensing of night lights with a focus on the limitations of current sensors, and provide an outlook for the future of remote sensing.
369 citations
Authors
Showing all 93441 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jing Wang | 184 | 4046 | 202769 |
Jiaguo Yu | 178 | 730 | 113300 |
Lei Jiang | 170 | 2244 | 135205 |
Gang Chen | 167 | 3372 | 149819 |
Omar M. Yaghi | 165 | 459 | 163918 |
Xiang Zhang | 154 | 1733 | 117576 |
Yi Yang | 143 | 2456 | 92268 |
Thomas P. Russell | 141 | 1012 | 80055 |
Jun Chen | 136 | 1856 | 77368 |
Lei Zhang | 135 | 2240 | 99365 |
Chuan He | 130 | 584 | 66438 |
Han Zhang | 130 | 970 | 58863 |
Lei Zhang | 130 | 2312 | 86950 |
Zhen Li | 127 | 1712 | 71351 |
Chao Zhang | 127 | 3119 | 84711 |