York University

About: York University is a education organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Population & Politics. The organization has 18899 authors who have published 43357 publications receiving 1568560 citations.

Variant mitoses in lower eukaryotes: indicators of the evolution of mitosis.

Abstract: Publisher Summary Mitosis is defined as all those types of nuclear division that produce two, or rarely more, daughter nuclei, each containing a chromosome complement approximately similar to that of the original nucleus. The greatest range of variations by which mitosis is accomplished, occurs in the protistan and fungal kingdoms, some members of which are probably most similar to the ancestors of higher plants and animals. The variations in the higher organisms are secondarily derived from the division patterns of typical plants and animals. This chapter discusses the characteristics and evolution of mitosis. The efficiency of mitosis consists of two basic components; the frequency with which each daughter nucleus receives the necessary complete genome complement (genetic efficiency) and the amount of energy and materials expended in the synthesis and operation of the mitotic apparatus. The chapter also discusses the use of mitosis as a phylogenetic marker. It is applicable to all eukaryotic cells and thus is valuable across boundaries where other structures are absent on one side and present in various forms on the other side.

PPARγ coactivator-1α expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations

Abstract: The transcriptional coactivator the peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) has been identified as an important mediator of mitochondrial biogenesis based on its abilit...

Corporate social responsibility and developing countries moving the critical CSR research agenda in Africa forward

Abstract: The criticism that the mainstream corporate social responsibility (CSR) agenda was largely driven by the concerns and priorities of western countries and therefore tends to be insensitive to local priorities as well as inadvertently harm prospects for sustainable livelihood in developing countries set the tone for the emergence of a South-centred CSR agenda. The efforts to broaden the scope and content of mainstream CSR discourse and practice has meant three principal themes have come to dominate the emerging South-centred critical CSR agenda. The emergence of this critical perspective to CSR has not only contributed to the maturation of contemporary CSR agenda but has also generated rich insights with regard to the strengths and limitations of CSR practices within developing countries. However, the failure to critically engage with the role of government, adopt a bottom-up approach to CSR analysis and avoid a piecemeal research focus has meant the emerging Southern perspective to CSR is yet to achieve it...