A simple method for the isolation and purification of total lipides from animal tissues.
TLDR
In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.About:
This article is published in Journal of Biological Chemistry.The article was published on 1957-05-01 and is currently open access. It has received 59550 citations till now. The article focuses on the topics: Triglyceride transport.read more
Citations
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Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats.
TL;DR: It is demonstrated that tea catechins exert a hypocholesterolemic effect in cholesterol-fed rats and increases fecal excretion of total lipids and cholesterol.
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The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation.
TL;DR: NADPH-dependent lipid peroxidation occurs in two distinct sequential radical steps, initiation and propagation, which results in the rapid formation of thiobarbituric acid-reactive material and lipid hydroperoxides.
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Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells
TL;DR: Probiotic treatment significantly improved the high fat diet-induced hepatic NKT cell depletion, insulin resistance and hepatic steatosis, and led to an improved sensitivity in insulin signaling.
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Hepatic lipid peroxidation in vivo in rats with chronic iron overload.
TL;DR: The presence of conjugated dienes in the subcellular fractions of rat liver provide direct evidence of iron-induced hepatic mitochondrial and microsomal lipid peroxidation in vivo in two models of experimental chronic iron overload.
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Intracellular Trafficking of Cholesterol Monitored with a Cyclodextrin
Edward B. Neufeld,Adele Cooney,Josef Pitha,Eliezar A. Dawidowicz,Nancy K. Dwyer,Peter G. Pentchev,E. Joan Blanchette-Mackie +6 more
TL;DR: Biochemical and cytochemical studies reveal that cyclodextrin specifically removes plasma membrane cholesterol, and attenuated esterification of lysosomal cholesterol in Niemann-Pick C cells reflects defective translocation of cholesterol to the plasma membrane that may be linked to abnormal Golgi trafficking.
References
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Preparation of lipide extracts from brain tissue.
TL;DR: A simple method is described for the preparation of extracts of total pure lipides from brain tissue by homogenizing the tissue with a chloroform-methanol mixture and washing free of non-lipide contaminants.
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Proteolipides, a new type of tissue lipoproteins; their isolation from brain.
Jordi Folch,Marjorie B. Lees +1 more
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The quantitative estimation of cerebrosides in nervous tissue.
TL;DR: The values for cerebrosides found in the current literature include gangliosides, and other investigators (JOHNSON, MCNABB, and ROSSITER, 1950; CUMINGS, 1953; BLACKWOOD and CUMings, 1954) have neglected the ganglariosides.
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Isolation of brain strandin, a new type of large molecule tissue component.
Jordi Folch,S. Arsove,J.A. Meath +2 more
TL;DR: The isolation from brain tissue of a substance to which the name of strandin has been given for descriptive purposes is reported, which has the property of forming long strands that show perfect orientation under polarized light.
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