Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
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Combined toxicity of graphene oxide and wastewater to the green alga Chlamydomonas reinhardtii
Idoia Martín-de-Lucía,Marina Celia Campos-Mañas,Ana Agüera,Francisco Leganés,Francisca Fernández-Piñas,Roberto Rosal +5 more
TL;DR: The results show that non-additive interactions at low effect levels cannot be generally neglected and that cells exposed to GO–wastewater mixtures were considerably less affected with lower or non-significant damage in comparison with GO or wastewater alone.
Journal ArticleDOI
Exploring biological effects of MoS2 nanosheets on native structures of α-helical peptides
TL;DR: The strong attraction from the MoS2 nanosheet is more than enough to compensate the energy needed to unfold the peptide, regardless of the length, which induces drastic disruptions to the intra-peptide hydrogen bonds and subsequent secondary structures of α - helices.
Journal ArticleDOI
Graphene oxide-silver nanocomposites modulate biofilm formation and extracellular polymeric substance (EPS) production.
Shima Liu,Shima Liu,Shuting Cao,Jingyang Guo,Jingyang Guo,Liqiang Luo,Yi Zhou,Chenglie Lin,Jiye Shi,Chunhai Fan,Min Lv,Lihua Wang +11 more
TL;DR: It is found that GO-AgNPs prevented biofilm formation in a dose-dependent manner, with a threshold of 15 μg mL-1, and caused bacterial death via both physical damage and oxidative stress, showing the synergic action of GO and AgNPs.
Journal ArticleDOI
In situ fabrication of green reduced graphene-based biocompatible anode for efficient energy recycle.
TL;DR: Green reduced graphene nanocomposite was successfully coated using layer-by-layer assembly technique onto carbon brush anode and has the potential to generate a high performing anode in further applications of MFCs.
Journal ArticleDOI
Fabrication of cotton fabrics through in-situ reduction of polymeric N-halamine modified graphene oxide with enhanced ultraviolet-blocking, self-cleaning, and highly efficient, and monitorable antibacterial properties
TL;DR: In this paper, a graphene oxide modified polymeric N-halamine precursor was coated onto cotton fabrics through a conventional "dipping-drying" method, and the functionalized cotton fabrics were in-situ reduced by treating with Lascorbic acid.
References
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TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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