Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
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Antifungal and Antibacterial Properties of Graphene-based Nanomaterials: A Mini-review
TL;DR: This review summarized the latest progresses towards an understanding of the antifungal and antibacterial properties of GBNs for developing a new antif fungus and antimicrobial nanomaterials.
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Atomic-engineered gold@silvergold alloy nanoflowers for in vivo inhibition of bacteria.
TL;DR: Application of Au@AgAu ANFs in the treatment of bacterial infections in the mouse intestine significantly reduces the reproduction of bacteria compared to an untreated mouse, giving results similar to those of the current antibiotic treatment, with no cytotoxicity.
Journal ArticleDOI
Understanding the Synergic Mechanism of Weak Interactions between Graphene Oxide and Lipid Membrane Leading to the Extraction of Lipids
TL;DR: Graphene oxide and lipid membrane is selected as a nano-bio model, and interaction forces at GO-biomembrane are modulated by varying amounts and species of oxygenated functional groups on the surface of GO.
Journal ArticleDOI
Function of c-type cytochromes of Shewanella xiamenensis in enhanced anaerobic bioreduction of Cr(VI) by graphene oxide and graphene oxide/polyvinyl alcohol films
Yixin Li,Zheng Chen,Zheng Chen,Yanyan Shi,Qingliu Luo,Yiming Wang,Honghui Wang,Yajuan Peng,Haitao Wang,Ning He,Yuanpeng Wang +10 more
TL;DR: A synergetic mechanism stimulated by GO-based materials to enhance Cr(VI) bioreduction that was not only mediated through the modification of material but also upregulated the expression of functional genes is disclosed.
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Effects of Boron Nitride Nanotube on the Secondary Structure of Aβ(1-42) Trimer: Possible Inhibitory Effect on Amyloid Formation
Nidhi Sorout,Amalendu Chandra +1 more
TL;DR: The current study reveals that the less hydrophobicity of BNNT provides stability of the initial secondary structure of the A-beta(1-42) trimer and hinder their aggregation.
References
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