Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
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Blend-electrospun graphene oxide/Poly(vinylidene fluoride) nanofibrous membranes with high flux, tetracycline removal and anti-fouling properties
Jeong-Ann Park,Aram Nam,Aram Nam,Jae Hyun Kim,Seong Taek Yun,Jae Woo Choi,Jae Woo Choi,Sang Hyup Lee,Sang Hyup Lee +8 more
TL;DR: Graphene oxide (GO)/poly(vinylidene fluoride) (PVDF) electrospun nanofibrous membranes (ENMs) have been fabricated to remove tetracycline (TC) from water via adsorptive-filtration as mentioned in this paper.
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Nanozymes used for antimicrobials and their applications
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Molecular-scale Hydrophilicity Induced by Solute: Molecular-thick Charged Pancakes of Aqueous Salt Solution on Hydrophobic Carbon-based Surfaces
TL;DR: Molecular-scale hydrophilicity induced by Solute: Molecular-thick charged pancakes of aqueous salt solution on Hydrophobic Carbon-based Surfaces.
Journal ArticleDOI
Fabrication of superhydrophobic titanium surfaces with superior antibacterial properties using graphene oxide and silanized silica nanoparticles
S.C. Vanithakumari,Geetisubhra Jena,Geetisubhra Jena,S. Sofia,C. Thinaharan,Rani P. George,John Philip,John Philip +7 more
TL;DR: In this paper, a new approach was proposed to create robust superhydrophobic (SHP) Ti surfaces with superior antibacterial property, using silane containing silica nanoparticles (Si np) functionalized Graphene oxide (GO).
Journal ArticleDOI
Dispersed graphene materials of biomedical interest and their toxicological consequences.
TL;DR: This review summarizes advancements in synthetic approaches and strategies of stabilizing graphene derivatives in aqueous medium and describes the interaction of colloidal graphene with cellular and sub-cellular components, and subsequent physiological signaling.
References
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TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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