Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
Citations
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The antimicrobial activity of nanoparticles: present situation and prospects for the future
TL;DR: The antibacterial mechanisms of NPs against bacteria and the factors that are involved are discussed and the limitations of current research are discussed.
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Environmental applications of graphene-based nanomaterials.
TL;DR: This critical review assesses the recent developments in the use of graphene-based materials as sorbent or photocatalytic materials for environmental decontamination, as building blocks for next generation water treatment and desalination membranes, and as electrode materials for contaminant monitoring or removal.
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Antifouling membranes for sustainable water purification: strategies and mechanisms
TL;DR: This review will first introduce the major foulants and the principal mechanisms of membrane fouling, and then highlight the development, current status and future prospects of antifouling membranes, including ant ifouling strategies, preparation techniques and practical applications.
Journal ArticleDOI
A review on mechanics and mechanical properties of 2D materials—Graphene and beyond
Deji Akinwande,Christopher J. Brennan,J. Scott Bunch,Philip Egberts,Jonathan R. Felts,Huajian Gao,Rui Huang,Joon-Seok Kim,Teng Li,Yao Li,Kenneth M. Liechti,Nanshu Lu,Harold S. Park,Evan J. Reed,Peng Wang,Boris I. Yakobson,Teng Zhang,Yong-Wei Zhang,Yao Zhou,Yong Zhu +19 more
TL;DR: A review of recent theoretical and experimental works related to mechanics and mechanical properties of 2D materials can be found in this article, where the authors show that there is a continual growth of interest in the mechanics of other two-dimensional materials beyond graphene.
Journal ArticleDOI
Antibacterial Activity of Ti3C2Tx MXene
TL;DR: The antibacterial properties of single- and few-layer Ti3C2Tx MXene flakes in colloidal solution were investigated and showed a higher antibacterial efficiency toward both Gram-negative E. coli and Gram-positive B. subtilis compared with graphene oxide (GO), which has been widely reported as an antibacterial agent.
References
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Dmitry V. Kosynkin,Amanda L. Higginbotham,Alexander Sinitskii,Jay R. Lomeda,Ayrat M. Dimiev,B. Katherine Price,James M. Tour +6 more
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Posted Content
PEGylated Nano-Graphene Oxide for Delivery of Water Insoluble Cancer Drugs
TL;DR: In this article, the authors functionalized nano-graphene oxide (NGO), a novel graphitic material, with branched polyethylene glycol (PEG) to obtain a biocompatible NGO-PEG conjugate stable in various biological solutions, and used them for attaching hydrophobic aromatic molecules including a camptothecin analog, SN38 non-covalently via pi-pi stacking.
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