Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
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Journal ArticleDOI
Oxidation and degradation of graphitic materials by naphthalene-degrading bacteria.
Lin Liu,Chunlin Zhu,Mengmeng Fan,Chuntao Chen,Yang Huang,Qingli Hao,Jiazhi Yang,Haiyan Wang,Dongping Sun +8 more
TL;DR: The ability of naphthalene-degrading bacteria to oxidize and degrade the graphitic materials shows the potential for producing GO in an eco-friendly way and degrading carbon nanomaterials in the environment.
Journal ArticleDOI
Layer-by-layer assembly of magnetic-core dual quantum dot-shell nanocomposites for fluorescence lateral flow detection of bacteria
Chongwen Wang,Chongwen Wang,Wanzhu Shen,Zhen Rong,Xiaoxian Liu,Bing Gu,Rui Xiao,Shengqi Wang,Shengqi Wang +8 more
TL;DR: A highly sensitive and quantitative fluorescent LFA strip for bacterial detection by using novel magnetic-core@dual quantum dot (QD)-shell nanoparticles (Fe3O4@DQDs) as multifunctional fluorescent labels for the quantitative detection of bacteria is reported.
Journal ArticleDOI
Terms of endearment: Bacteria meet graphene nanosurfaces.
E. Tegou,Maria Magana,Alexandra Eleni Katsogridaki,Anastasios Ioannidis,Vasilios Raptis,Sheldon Jordan,Stylianos Chatzipanagiotou,Stavros Chatzandroulis,Catia Ornelas,George P. Tegos +9 more
TL;DR: An overview on paradigms of graphene-microbial interactions is expected to shed light on the range of materials available, and identify possible applications, serving the ultimate goal to develop deeper understanding and collective conscience for the true capabilities of this nanomaterial platform.
Journal ArticleDOI
Multidimensional graphene structures and beyond: Unique properties, syntheses and applications
TL;DR: Graphene is a single carbon layer of zero bandgap without edges and basal plane fluctuations as discussed by the authors, which can be classified into low-dimensional or hierarchical structures as well as novel functionalities.
Journal ArticleDOI
A Review of Patterned Organic Bioelectronic Materials and their Biomedical Applications
TL;DR: An overview of the unique properties of organic bioelectronic materials, different strategies applied to pattern these materials, and finally their applications in the field of biomedical engineering, particularly biosensing, cell and tissue engineering, actuators, and drug delivery are provided.
References
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Journal ArticleDOI
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Understanding biophysicochemical interactions at the nano–bio interface
Andre E. Nel,Lutz Mädler,Darrell Velegol,Tian Xia,Eric M.V. Hoek,Ponisseril Somasundaran,Fred Klaessig,Vince Castranova,Mike Thompson +8 more
TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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