Journal ArticleDOI
Destructive extraction of phospholipids from Escherichia coli membranes by graphene nanosheets
Yusong Tu,Min Lv,Peng Xiu,Tien Huynh,Meng Zhang,Matteo Castelli,Z. Y. Liu,Qing(黄庆) Huang,Chunhai(樊春海) Fan,Haiping(方海平) Fang,Ruhong Zhou,Ruhong Zhou,Ruhong Zhou +12 more
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TLDR
Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules as mentioned in this paper.Abstract:
Understanding how nanomaterials interact with cell membranes is related to how they cause cytotoxicity and is therefore critical for designing safer biomedical applications. Recently, graphene (a two-dimensional nanomaterial) was shown to have antibacterial activity on Escherichia coli, but its underlying molecular mechanisms remain unknown. Here we show experimentally and theoretically that pristine graphene and graphene oxide nanosheets can induce the degradation of the inner and outer cell membranes of Escherichia coli, and reduce their viability. Transmission electron microscopy shows three rough stages, and molecular dynamics simulations reveal the atomic details of the process. Graphene nanosheets can penetrate into and extract large amounts of phospholipids from the cell membranes because of the strong dispersion interactions between graphene and lipid molecules. This destructive extraction offers a novel mechanism for the molecular basis of graphene's cytotoxicity and antibacterial activity.read more
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Can carbon-based nanomaterials revolutionize membrane fabrication for water treatment and desalination?
Yehia Manawi,Victor Kochkodan,Muataz Ali Hussein,Moe A. Khaleel,Marwan K. Khraisheh,Nidal Hilal +5 more
TL;DR: A review of the current state of the application of carbon-based nanomaterials, including carbon nanotubes, graphene, graphene oxide, carbon nanofibers, MXene, carbide derived carbon and fullerene for membrane preparation is provided in this paper.
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Hierarchical Multicomponent Inorganic Metamaterials: Intrinsically Driven Self-Assembly at the Nanoscale.
TL;DR: Inspired by the fictional Baron Munchausen's fruitless attempt to pull himself up, it is demonstrated that metamaterials can undergo intrinsically driven self-assembly, metaphorically pulling themselves up into existence.
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Effect of exogenous carbonaceous materials on the bioavailability of organic pollutants and their ecological risks
Xiaoya Ren,Guangming Zeng,Lin Tang,Jingjing Wang,Jia Wan,Haopeng Feng,Biao Song,Chao Huang,Xiang Tang +8 more
TL;DR: In this paper, the authors present an overview on how exogenous carbonaceous materials (ECMs) affect bioavailability of organic pollutants to different organisms, such as microorganisms, plants and earthworms.
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Antimicrobial Nano-Agents: The Copper Age.
TL;DR: In this paper, the authors present a critical review on the state of the art regarding the in vitro and in vivo evaluations of the antimicrobial activity of copper-based nanoparticles together with absorption, distribution, metabolism, excretion, and toxicity assessments.
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Cytotoxicity of graphene: recent advances and future perspective
TL;DR: These studies have provided a better understanding of graphene nanotoxicity at both cellular and molecular levels, and also suggested therapeutic potential by using graphene's cytotoxicity against bacteria cells.
References
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TL;DR: This review analyzes recent trends in graphene research and applications, and attempts to identify future directions in which the field is likely to develop.
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
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Understanding biophysicochemical interactions at the nano–bio interface
Andre E. Nel,Lutz Mädler,Darrell Velegol,Tian Xia,Eric M.V. Hoek,Ponisseril Somasundaran,Fred Klaessig,Vince Castranova,Mike Thompson +8 more
TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
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