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Gout

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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.

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Comprehensive review on therapeutic strategies of gouty arthritis.

TL;DR: The present article deals with the therapeutic strategies and options for the cure of gouty arthritis by analyzing classical textbooks and peer reviewed papers, consulting worldwide accepted scientific databases.
Journal ArticleDOI

Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1

TL;DR: ChondroT displayed anti-hyperuricemic effects by regulating XOD activity and kidney mURAT1 by regulating xanthine oxidase activity in a dose-dependent manner and showing significant anti-arthritis and anti-inflammatory effects.
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Comparison of activity indexes for recognizing enzyme mutants of higher activity with uricase as model.

TL;DR: Specific activity calculated from the level of total proteins is a favorable index for recognizing an enzyme mutant with small improvement of activity.
Journal ArticleDOI

Interventions for tophi in gout

TL;DR: Moderate-quality evidence from one study indicated that biweekly pegloticase 8 mg infusion reduced tophi in the subset of participants with tophi, but increased withdrawals due to adverse events in all participants, and monthly infusion appeared to result in less benefit.
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Could MicroRNAs be Regulators of Gout Pathogenesis

TL;DR: The present review systemically discusses relevant publications in order to provide a better understanding on the possible role of miRNAs in gout to suggest a promising strategy in the treatment of gout.
References
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Book

The Metabolic and Molecular Bases of Inherited Disease

TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
Book

A Laboratory manual

M. Ashburner
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.
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