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Gout

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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.

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Dose-response association of uncontrolled blood pressure and cardiovascular disease risk factors with hyperuricemia and gout.

TL;DR: With one in three people affected by hyperuricemia among those with several CVD risk factors, physicians should consider their anti-hypertensive regimens carefully and potentially screen for hyperuricaemia or gout.
Journal ArticleDOI

Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout.

TL;DR: Routine testing for HLA-B*58:01 in order to reduce the incidence of adverse drug reactions in patients being prescribed allopurinol for gout is unlikely to be cost- effective in the UK; however testing is expected to become cost-effective with reductions in the cost of genotyping, and with the future availability of cheaper, generic febuxostat.
Journal ArticleDOI

Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study.

TL;DR: Replicating the methods used to demonstrate an association of SUA with carotid Atherosclerosis did not reveal any association between SUA and CAC, suggesting that SUA likely does not contribute to atherosclerosis through effects on arterial calcification.
Journal ArticleDOI

The effect of bariatric surgery on gout: a comparative study

TL;DR: The frequency of early postoperative gout attacks after bariatric surgery is significantly higher than that of patients undergoing other procedures, however, the incidence decreases significantly after the first postoperative month up to 1 year.
Journal ArticleDOI

Changes in toll-like receptor (TLR)4–NFκB–IL1β signaling in male gout patients might be involved in the pathogenesis of primary gouty arthritis

TL;DR: TLR4–NFκB-interleukin1β–IL1β signaling might play a crucial role in the development of acute inflammation in primary gout patients.
References
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Book

The Metabolic and Molecular Bases of Inherited Disease

TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
Book

A Laboratory manual

M. Ashburner
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.
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