Gout
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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.read more
Citations
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Journal ArticleDOI
Modeling human Coenzyme A synthase mutation in yeast reveals altered mitochondrial function, lipid content and iron metabolism
Camilla Ceccatelli Berti,Cristina Dallabona,Mirca Lazzaretti,Sabrina Dusi,Elena Tosi,Valeria Tiranti,Paola Goffrini +6 more
TL;DR: In this article, mutations in nuclear genes associated with defective coenzyme A biosynthesis have been identified as responsible for some forms of neurodegeneration with brain iron accumulation (NBIA), namely PKAN and CoPAN.
Journal ArticleDOI
DHA protects against monosodium urate-induced inflammation through modulation of oxidative stress.
Yue Zhang,Yue Zhang,Lu Liu,Dongzhe Sun,Yongjing He,Yue Jiang,Ka-Wing Cheng,Ka-Wing Cheng,Feng Chen,Feng Chen +9 more
TL;DR: The results suggest that DHA or DHA-rich microalgal oil may be a promising natural agent for the prevention of MSU-induced inflammation and potentially acute gout at least partly by attenuating oxidative stress.
Journal ArticleDOI
The lack of association between the burden of monosodium urate crystals assessed with dual-energy computed tomography or ultrasonography with cardiovascular risk in the commonly high-risk gout patient
Tristan Pascart,Benoist Capon,Agathe Grandjean,J. Legrand,Nasser Namane,Vincent Ducoulombier,Marguerite Motte,Marie Vandecandelaere,Hélène Luraschi,Catherine Godart,Eric Houvenagel,Laurène Norberciak,Jean-François Budzik +12 more
TL;DR: The extent of MSU burden does not increase the estimated risk of cardiovascular events in gout patients, and DECT MSU deposit volume was similar in patients with and without metabolic syndrome.
Journal ArticleDOI
Looking for new xanthine oxidase inhibitors: 3-Phenylcoumarins versus 2-phenylbenzofurans.
Benedetta Era,Giovanna Delogu,Francesca Pintus,Antonella Fais,Gianluca Gatto,Eugenio Uriarte,Fernanda Borges,Amit Kumar,Maria João Matos,Maria João Matos +9 more
TL;DR: This work is a preliminary screening for further design and synthesis of new non-purinergic derivatives as potential compounds involved in the inflammatory suppression, specially related to gout.
Journal ArticleDOI
Xanthine Oxidase Inhibitory Activity and Antigout of Celery Leek Parsley and Molokhia
TL;DR: The results showed that increasing serum total calcium level with extracts of celery, leek, parsley, and molokhia in comparison to positive control has some protective effects on the gout.
References
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Book
The Metabolic and Molecular Bases of Inherited Disease
TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
Journal ArticleDOI
2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
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A Laboratory manual
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.