Gout
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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.read more
Citations
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2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia
Dinesh Khanna,John FitzGerald,Puja P. Khanna,Sangmee Bae,Manjit K. Singh,Tuhina Neogi,Michael H. Pillinger,Joan Merill,Susan J. Lee,Shraddha Prakash,Marian Kaldas,Maneesh Gogia,Fernando Perez-Ruiz,William J. Taylor,Frédéric Lioté,Hyon K. Choi,Jasvinder A. Singh,Nicola Dalbeth,Sanford Kaplan,Vandana Dua Niyyar,Danielle Jones,Steven A. Yarows,Blake J. Roessler,Gail S. Kerr,Charles H. King,Gerald Levy,Daniel E. Furst,N. Lawrence Edwards,Brian F. Mandell,H. Ralph Schumacher,Mark L. Robbins,Neil S. Wenger,Robert Terkeltaub +32 more
TL;DR: DINESH KHanNA, JOHN D. FITZGERALD, PUJA P. KHANNA, SANGMEE BAE, MANJIT K. SINGH, TUHINA NEOGI, MICHAEL H. PILLINGER, JOAN MERILL, SUSAN LEE, SHRADDHA PRAKASH, MARIAN KALDAS, MANEESH GOGIA, FERNANDO PEREZ-RUI
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Sugar-sweetened beverages and risk of obesity and type 2 diabetes: Epidemiologic evidence
Frank B. Hu,Vasanti S. Malik +1 more
TL;DR: It is thought that SSBs contribute to weight gain in part by incomplete compensation for energy at subsequent meals following intake of liquid calories, and should be replaced by healthy alternatives such as water, to reduce risk of obesity and chronic diseases.
Journal ArticleDOI
Uric acid transport and disease.
Alexander So,Bernard Thorens +1 more
TL;DR: The biology of urate metabolism and its role in disease is discussed and recent studies identifying SLC2A9, which encodes the glucose transporter family isoform Glut9, as a major determinant of plasma uric acid levels and of gout development are identified.
Journal ArticleDOI
A Broader View: Microbial Enzymes and Their Relevance in Industries, Medicine, and Beyond
TL;DR: In this review, an approach has been made to highlight the importance of different enzymes with special emphasis on amylase and lipase in the different industrial and medical fields.
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Where is mTOR and what is it doing there
Charles Betz,Michael N. Hall +1 more
TL;DR: The finding that mTORC1 is localized to the lysosome has significantly enhanced the understanding of m TORC1 regulation and may be a general principle used by TOR to enact precise spatial and temporal control of cell growth.
References
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Patient-reported outcomes in chronic gout: a report from OMERACT 10.
Jasvinder A. Singh,William J. Taylor,Lee S. Simon,Puja P. Khanna,Lisa K. Stamp,Fiona M McQueen,Tuhina Neogi,Angelo L. Gaffo,Michael Becker,Patricia A. MacDonald,Omar Dabbous,Vibeke Strand,Nicola Dalbeth,Daniel Aletaha,N. Lawrence Edwards,H. Ralph Schumacher +15 more
TL;DR: All 4 PRO for chronic gout have been endorsed with the endorsement of one measure each for pain, patient global, SF-36, and activity limitation, and future validation studies are needed for the disease-specific measure, GAQ v2.0.
Journal ArticleDOI
Gout: an evidence-based review.
Lan X. Chen,H. Ralph Schumacher +1 more
TL;DR: A review of recent developments related to gout epidemiology, pathogenesis, diagnosis, and efficacy of existing therapies identifies evidence, persisting gaps in evidence, and address clinical implications.
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Trends in serum uric acid levels
TL;DR: Preliminary data available from a fourth examination indicate that the rising trend in uric acid levels of adult male volunteers in a longitudinal study of human aging has leveled off.
Journal ArticleDOI
Hyperuricemia in Hyperparathyroidism
TL;DR: The recent experiences with hyperparathyroid subjects suggests that the association of hyperuricemia and functioning parathyroid adenomas is not infrequent, and the further demonstration of a surprising incidence of gout in these subjects bears emphasis.