Gout
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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.read more
Citations
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Journal ArticleDOI
Identification of the urine and serum metabolomics signature of gout.
Yefei Huang,Min Xiao,Jiayong Ou,Qing Lv,Qiujing Wei,Zena Chen,Jialing Wu,Liudan Tu,Yutong Jiang,Xi Zhang,Jun Qi,M. Qiu,Shuangyan Cao,Jieruo Gu +13 more
TL;DR: The metabolomics signatures could serve as an efficient tool for early diagnosis and provide novel insights into the pathogenesis of gout.
Journal ArticleDOI
Allopurinol and xanthine use different translocation mechanisms and trajectories in the fungal UapA transporter.
TL;DR: Genetic and physiological evidence and genetic evidence suggest that the allopurinol translocation pathway is distinct from, but probably overlapping with, that of physiological UapA substrates, and evidence was obtained supporting that accelerated influx of xanthine is triggered through exchange with cytoplasmically accumulated allopURinol.
Journal ArticleDOI
How clinical and research failures lead to suboptimal prescribing: the example of chronic gout
TL;DR: Despite the existence of several effective drugs for chronic tophaceous gout, management is often neither rational nor effective, according to Wendy Lipworth and colleagues.
Journal ArticleDOI
Is there a role for cherries in the management of gout
TL;DR: Cherries have antioxidant and anti-inflammatory properties, which may reduce both the acute and chronic inflammation associated with recurrent gout flares and its chronic destructive arthropathy.
Journal ArticleDOI
Association of hyperuricemia with disease severity in chronic hepatitis C patients
Tyng-Yuan Jang,Ming-Lun Yeh,Ching-I Huang,Zu-Yau Lin,Shinn-Cherng Chen,Meng-Hsuan Hsieh,Chia-Yen Dai,Jee-Fu Huang,Chung-Feng Huang,Wan-Long Chuang,Ming-Lung Yu +10 more
TL;DR: Hyperuricemia was inversely associated with liver disease severity in CHC male patients, and the factors associated with this condition included BMI, glomerular filtration rate, and eGFR.
References
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Book
The Metabolic and Molecular Bases of Inherited Disease
TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
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2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
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A Laboratory manual
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.