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Gout

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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.

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Journal ArticleDOI

Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study.

TL;DR: The TLR4 gene rs2149356 SNP might be associated with gouty arthritis susceptibility, and might participate in regulating immune, inflammation and lipid metabolism.
Journal ArticleDOI

Anti-hyperuricemic peptides derived from bonito hydrolysates based on in vivo hyperuricemic model and in vitro xanthine oxidase inhibitory activity

TL;DR: Hexapeptide PGACSN and tripeptide WML are partially responsible for the anti‐hyperuricemic activity of BH, and hydrophobic amino acids play important roles in the XOD inhibitory activity of peptides.
Journal ArticleDOI

The anatomical pathology of gout: a systematic literature review

TL;DR: Most studies describing the anatomical pathology of gout report involvement of musculoskeletal structures, with monosodium urate crystal deposition and tophus the most common lesions described.
Journal ArticleDOI

Imaging Appearances in Gout

TL;DR: The presence of a combination of the ultrasound findings of an effusion, tophus, erosion and the double contour sign in conjunction with clinical presentation may be able to obviate the need for intervention and joint aspiration in a certain case population for the diagnosis of gout.
Journal ArticleDOI

Genetic association between adiposity and gout: a Mendelian randomization study.

TL;DR: Support is provided that overall obesity may be a risk factor for gout and is associated with higher serum urate concentrations, and genetically higher BMI, but not waist-to-hip ratio adjusted for BMI, was positively associated with risk of gout.
References
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Book

The Metabolic and Molecular Bases of Inherited Disease

TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
Book

A Laboratory manual

M. Ashburner
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.
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