Gout
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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.read more
Citations
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Journal ArticleDOI
Variants of ALPK1 with ABCG2, SLC2A9, and SLC22A12 increased the positive predictive value for gout.
Hung-Pin Tu,Albert Min-Shan Ko,Su-Shin Lee,Chi-Pin Lee,Tzer-Min Kuo,Chung-Ming Huang,Ying-Chin Ko +6 more
TL;DR: Combined exposure to the four high-risk genotypes of ALPK1 and the uric-acid-related loci of ABCG2, SLC2A9, and SLC22A12 was associated with an increased gout risk and a high PPV for gout.
Journal ArticleDOI
Structural Joint Damage in Gout
Ashika Chhana,Nicola Dalbeth +1 more
TL;DR: The structural damage that is observed in advanced gout and current understanding of the mechanisms by which this damage occurs are summarized.
Journal ArticleDOI
Early-life exposure to the Chinese famine of 1959-61 and risk of Hyperuricemia: results from the China health and retirement longitudinal study.
Wenqiang Zhang,Rongsheng Luan +1 more
TL;DR: Famine exposure in the fetal stage was associated with an increased risk of hyperuricemia in adulthood, and combined unexposed and early-childhood exposed participants as an age-balanced control showed no change.
Journal ArticleDOI
Anti-inflammatory Effect of Total Saponin Fraction from Dioscorea nipponica Makino on Gouty Arthritis and Its Influence on NALP3 Inflammasome.
TL;DR: Dioscorea nipponica may treat GA by regulating lysosomal enzymes, antioxidant capacities and the NALP3 inflammasome by regulating the activities of β-galactosidase,β-N acetyl glucosamine enzyme, β-glucuronidases, acid phosphatase, and malonaldehyde.
Journal ArticleDOI
Hypouricemic Effect of 2,5-Dihydroxyacetophenone, a Computational Screened Bioactive Compound from Ganoderma applanatum, on Hyperuricemic Mice
Danling Liang,Yong Tianqiao,Shaodan Chen,Yizhen Xie,Diling Chen,Xinxin Zhou,Dan Li,Muxia Li,Lu Su,Dan Zuo +9 more
TL;DR: The hypouricemic effect of 2,5-dihydroxyacetophenone (DHAP) is reported, a compound screened from Ganoderma applanatum computationally that showed some kidney-protective effects and may be mediated by regulation of XOD, OAT1, GLUT9, URat1, and CNT2.
References
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Book
The Metabolic and Molecular Bases of Inherited Disease
TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
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2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
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A Laboratory manual
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.