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Gout

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This article is published in BMJ.The article was published on 2011-04-01 and is currently open access. It has received 729 citations till now.

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Journal ArticleDOI

Monosodium urate crystal-induced pro-interleukin-1β production is post-transcriptionally regulated via the p38 signaling pathway in human monocytes.

TL;DR: It is demonstrated that post-transcriptional regulation via p38 MAPK plays a central role in the rapid synthesis of pro-IL-1 β in response to MSU crystals, which is an essential step for IL-1β production in human monocytes.
Journal ArticleDOI

Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population.

TL;DR: The GG genotype of NLRP3 rs10754558 was found to be significantly associated with patients with GA compared to the healthy control subjects via multivariate logistic regression analysis and might participate in regulating immune and inflammation responses in patients withGA by influencing the expression of components of theNLRP3 inflammasome.
Journal ArticleDOI

Chinese herbal medicine for gout: a systematic review of randomized clinical trials

TL;DR: Chinese herbal medicine may have clinical effectiveness for functional recovery in patients with gout, and lead to a safe control of serum uric acid level and inflammation severity.
Journal ArticleDOI

Urate crystal deposition, prevention and various diagnosis techniques of GOUT arthritis disease: a comprehensive review

TL;DR: Imaging procedures have ended up being helpful for location of urate statement, even before the primary clinical indications, empowering the assessment of the degree of testimony and giving target estimation of precious stone exhaustion amid urate-bringing down treatment.
Journal ArticleDOI

Ulcerated tophaceous gout

TL;DR: Four cases of ulceration associated with gout tophi are described to highlight the clinical presentation, complications and a management strategy.
References
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Book

The Metabolic and Molecular Bases of Inherited Disease

TL;DR: In this paper, the authors present a list of disorders of MITOCHONDRIAL FUNCTION, including the following: DISORDERS OF MIOCHONDRIC FERTILITY XIX, XVI, XIX.
Book

A Laboratory manual

M. Ashburner
TL;DR: To develop a program to print the barcodes using two commonly uses command sets and hence evaluates their ease of use for such applications, students should be able to program dot matrix printers, by manipulating bit level information and ink jet printers using page description language, such as PCL.
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