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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Synthesis and characterization of in situ cross-linked hydrogel based on self-assembly of thiol-modified chitosan with PEG diacrylate using Michael type addition
TL;DR: A novel injectable in situ cross-linked hydrogel has been designed via Michael type addition between thiol-modified chitosan (CS–NAC) and PEG diacrylate (PEGDA) and the results indicated that the hydrogels was biocompatible.
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Photo-Cross-Linked PDMSstar-PEG Hydrogels: Synthesis, Characterization, and Potential Application for Tissue Engineering Scaffolds
Yaping Hou,Cody A. Schoener,Katherine R. Regan,Dany J. Munoz-Pinto,Mariah S. Hahn,Melissa A. Grunlan +5 more
TL;DR: This library of inorganic-organic hydrogels with tunable properties provides a useful platform to study the effect of scaffold properties on cell behavior and the swelling ratio, mechanical properties in tension and compression, and nonspecific protein adhesion were studied.
Journal ArticleDOI
Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogels
TL;DR: It was determined that polymer density had the most profound effect on protein diffusivity, followed by the polymer molecular weight, and finally by the specific chemical structure of the cross‐linker.
Journal ArticleDOI
Structure Optimization and Mechanical Model for Microgel-Reinforced Hydrogels with High Strength and Toughness
Jian Hu,Takayuki Kurokawa,Kenta Hiwatashi,Tasuku Nakajima,Zi Liang Wu,Song Miao Liang,Jian Ping Gong +6 more
TL;DR: In this paper, the mechanical behavior of sparsely crosslinked, neutral polyacrylamide (PAAm) hydrogels containing densely cross-linked polyelectrolyte microgels of poly(2-Acrylamido-2-methylpropanesulfonic sodium) (PNaAMPS) were studied systematically by varying the formulations.
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Developmental biology and tissue engineering.
TL;DR: Computer simulations support the idea that tissue liquidity may provide a mechanism for in vitro organ building and explain how the parameters (surface tension, viscosity) that govern tissue fusion can be used both experimentally and theoretically to control and simulate the self-assembly of cellular spheroids into 3D living structures.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.