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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Collagen cryogel cross-linked by naturally derived dialdehyde carboxymethyl cellulose

TL;DR: The in vitro blood-compatibility tests prove that the introduction of DCMC does not cause the reducing performance in hemolysis and blood clotting compared with pure collagen, and the low-cost and non-toxic nature ofDCMC confers the cryogel great potential in tissue engineering and other biomedical applications.
Journal ArticleDOI

High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology

TL;DR: High-throughput experimentation within the field of materiobiology enables the elucidation of the relationships between biomaterial properties and biological behavior and thereby serves as a potential tool for accelerating the development of high-performance biomaterials as mentioned in this paper.
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Catching a SPY: Using the SpyCatcher-SpyTag and Related Systems for Labeling and Localizing Bacterial Proteins

TL;DR: The current state of the SpyCatcher-SpyTag and related technologies are reviewed, with a particular emphasis on their use in vaccine development and in determining outer membrane protein localization and topology of surface proteins in bacteria.
Journal ArticleDOI

Biodegradable hydrogels based on novel photopolymerizable guar gum–methacrylate macromonomers for in situ fabrication of tissue engineering scaffolds

TL;DR: The degree of in vitro enzymatic biodegradation of the hydrogels decreased linearly with increasing gel content and the degree of methacrylation of the respective macromonomers.
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Mechanics of elastomeric molecular composites

TL;DR: A model system of molecular composites where the filler is a continuous network embedded into a stretchy matrix, and it is demonstrated that the elastomer undergoes a strong localized softening due to scission of covalent bonds followed by a stable necking process, a phenomenon never observed before in elastomers.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
Journal ArticleDOI

Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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