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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
TL;DR: This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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Journal ArticleDOI
Biomedical Applications of Chitin, Chitosan, and Their Derivatives
Dinesh K. Singh,Alok R. Ray +1 more
TL;DR: Using nanofiltration membranes for wound-Healing Accelerators and drug delivery systems for antimicrobial applications is shown to be a viable process.
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Mechanical influences on vascular smooth muscle cell function.
TL;DR: This review focuses on an emerging field of cardiovascular research in which the direct effects of mechanical strain on VSM cells and isolated blood vessels in organ culture have been characterized, in vitro.
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An osteoconductive collagen/hyaluronate matrix for bone regeneration.
TL;DR: When implanted in cranial defects in rats, the COL/HA matrix demonstrated good biocompatibility and exhibited greater osteoconductive potential than matrices composed of either cross-linked collagen or cross- linked hyaluronate alone.
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Photopolymerization of multilaminated poly(HEMA) hydrogels for controlled release
Sanxiu Lu,Kristi S. Anseth +1 more
TL;DR: The results indicate that a zero-order release pattern can be approximated by employing a suitable nonuniform initial drug concentration profile.
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Degradation behavior of covalently cross-linked poly(aldehyde guluronate) hydrogels
TL;DR: The degradation behavior of novel hydrogels formed by the cross-linking of poly(aldehyde guluronate) (PAG) is confirmed by monitoring the changes of dry weight, modulus, and degree of swelling.