Journal ArticleDOI
Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
Citations
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Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.
Jiang Wu,Zecong Xiao,Anqi Chen,Huacheng He,Chaochao He,Xintao Shuai,Xiaokun Li,Shengfu Chen,Yanxian Zhang,Baiping Ren,Jie Zheng,Jie Zheng,Jian Xiao,Jian Xiao +13 more
TL;DR: Collective results indicate that SBMA hydrogels promote full-thickness excisional acute wound regeneration in mice by enhancing angiogenesis, decreasing inflammation response, and modulating macrophage polarization, which improved the overall wound healing efficiency as compared to pure PEG hydrogel.
Journal ArticleDOI
Peptide-functionalized oxime hydrogels with tunable mechanical properties and gelation behavior
Fei Lin,Jiayi Yu,Wen Tang,Jukuan Zheng,Adrian P. Defante,Kai Guo,Chrys Wesdemiotis,Matthew L. Becker +7 more
TL;DR: These materials are the initial demonstration for translationally relevant hydrogel materials that possess tunable mechanical regimes attractive to soft tissue engineering and possess atom neutral chemistries attractive for post gelation patterning in the presence or absence of cells.
Journal ArticleDOI
Fracture of a biopolymer gel as a viscoplastic disentanglement process.
TL;DR: It is proposed that, in contrast with chemically cross-linked ones, reversible gels fracture without chain scission, because of the sensitivity of the elastic stiffness to gel composition and history.
Patent
Surface-independent, surface-modifying, multifunctional coatings and applications thereof
TL;DR: In this article, a surface-independent surface-modifying multifunctional biocoating and methods of application thereof are described, where a surface modifying agent (SMA) is used to modify the substrate surface to include at least one reactive moiety.
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Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices
Yanfen Li,Kristopher A. Kilian +1 more
TL;DR: How the field of engineered extracellular matrices has evolved with the development of new hydrogel chemistry and the maturation of micro‐ and nano‐ fabrication is explored.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI
Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.