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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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PatentDOI

Strain-promoted crosslinking of peg-based hydrogels via copper-free cycloaddition

TL;DR: In this article, a covalently crosslinked hydrogel comprising the strain-promoted reaction product of an 8-member cycloalkyne functionalized polyalkylene glycol and a multi-arm glycerol exytholate triazide was presented.
Journal ArticleDOI

Protein diffusion in agarose hydrogel in situ measured by improved refractive index method.

TL;DR: This paper improved the previous in situ refractive index method with great temperature-controlled capability to study the diffusion of protein (bovine serum albumin and lysozyme) in agarose hydrogel at body temperature.
Journal ArticleDOI

Structure Calculation of an Elastic Hydrogel from Sonication of Rigid Small Molecule Components

TL;DR: Calculations successfully predict the molecular structure of a robust hydrogel and successfully compared with powder X-ray diffraction data of the xerogel.
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Head group modulated pH-responsive hydrogel of amino acid-based amphiphiles: entrapment and release of cytochrome c and vitamin B12.

TL;DR: The rational design and synthesis of amino acid-based amphiphilic hydrogelators, which were systemically fine-tuned at the head group to develop pH-responsive hydrogels, have established the prospect of the hydrogEL as an efficient drug delivery vehicle.
Journal ArticleDOI

Status and future scope of hydrogels in wound healing: Synthesis, materials and evaluation

TL;DR: This review discusses materials used to produce hydrogels, focused on TCM-based hydrogel materials with bioactive properties that promote healing and methods for evaluating hydrogEL wound dressings are discussed to guide the preparation of new Hydrogels.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
Journal ArticleDOI

Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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