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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
TL;DR: This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.
Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Highly stretchable and tough hydrogels
Jeong-Yun Sun,Xuanhe Zhao,Widusha R. K. Illeperuma,Ovijit Chaudhuri,Kyu Hwan Oh,David J. Mooney,David J. Mooney,Joost J. Vlassak,Zhigang Suo +8 more
TL;DR: The synthesis of hydrogels from polymers forming ionically and covalently crosslinked networks is reported, finding that these gels’ toughness is attributed to the synergy of two mechanisms: crack bridging by the network of covalent crosslinks, and hysteresis by unzipping thenetwork of ionic crosslinks.
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New biodegradable polymers for injectable drug delivery systems
TL;DR: New star-shaped block copolymers, of which the typical molecular architecture is presented, results from their distinct solution properties, thermal properties and morphology, which provide unique behavior that sol (at low temperature) form gel (at body temperature).
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A new class of drug carriers: micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain☆
Alexander V. Kabanov,Elena V. Batrakova,N. S. Melik-Nubarov,Nikolai A. Fedoseev,Tatiyana Yu. Dorodnich,Valery Yu Alakhov,Vladimir P. Chekhonin,Irina R. Nazarova,Victor A. Kabanov +8 more
TL;DR: It was found that solubilization of FITC in pluronic micelles considerably influences its distribution in animal (mouse) tissues resulting, in particular, in the drastic increase of F ITC fluorescence in lung.
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Reinforced uncrosslinked poly (vinyl alcohol) gels produced by cyclic freezing-thawing processes: a short review
TL;DR: In this paper, the authors present methods of preparation of strong poly(vinyl alcohol) hydrogels without utilization of chemical crosslinking or reinforcing agents and discuss biomedical and pharmaceutical applications of these gels.
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Cell biology of hydrogels
TL;DR: It is shown that, similar to natural macromolecules of the extracellular matrix, the synthetic polymers are able to participate in the control of cell function.
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Synthesis and in vitro degradation of new polyvalent hydrazide cross-linked hydrogels of hyaluronic acid.
TL;DR: New polyvalent hydrazide cross-linkers were synthesized, characterized, and used to prepare hydrazid cross-linked hydrogels derived from hyaluronic acid (HA) with different chemical and physical properties.