Journal ArticleDOI
Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
Citations
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Injectable biodegradable hydrogels: progress and challenges
TL;DR: An overview of state-of-the-art strategies towards constructing a rational design of injectable biodegradable hydrogels for protein drug delivery and tissue engineering is provided.
Journal ArticleDOI
Microfluidic techniques for development of 3D vascularized tissue.
Anwarul Hasan,Anwarul Hasan,Anwarul Hasan,Arghya Paul,Nihal Engin Vrana,Xin Zhao,Adnan Memic,Yu-Shik Hwang,Mehmet R. Dokmeci,Ali Khademhosseini +9 more
TL;DR: This review presents an overview of the recent advancements in the vascularization techniques using both approaches for generating 3D vascular structure on microfluidic platforms.
Journal ArticleDOI
Anti-fatigue-fracture hydrogels
Shaoting Lin,Xinyue Liu,Ji Liu,Hyunwoo Yuk,Hyun-Chae Loh,German Alberto Parada,Charles Settens,Jake Song,Admir Masic,Gareth H. McKinley,Xuanhe Zhao +10 more
TL;DR: In this article, the authors demonstrate that the controlled introduction of crystallinity in hydrogels can substantially enhance their anti-fatigue-fracture properties and show that the fatigue threshold of polyvinyl alcohol (PVA) with a crystallinity of 18.9 weight % in the swollen state can exceed 1000 J/m2.
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Self-healable, super tough graphene oxide–poly(acrylic acid) nanocomposite hydrogels facilitated by dual cross-linking effects through dynamic ionic interactions
TL;DR: A facile, one-pot in situ free radical polymerization strategy to prepare self-healable, super tough graphene oxide (GO)-poly(acrylic acid) (PAA) nanocomposite hydrogels by using Fe3+ ions as a cross-linker is proposed.
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Chemically controlled closed-loop insulin delivery
TL;DR: This field of research is promising as a possible alternative to other approaches for diabetes treatment, and recent developments made represent significant progress in terms of biocompatibility, selectivity, pharmacokinetics, and easiness of administration.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.