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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Composite three-dimensional woven scaffolds with interpenetrating network hydrogels to create functional synthetic articular cartilage.

TL;DR: A three‐dimensionally woven fiber scaffold that is infiltrated with an interpenetrating network hydrogel can build a functional biomaterial that provides the load‐bearing and tribological properties of native cartilage.
Journal ArticleDOI

Self-assembled amino acids and dipeptides as noncovalent hydrogels for tissue engineering

TL;DR: This review will critically assess current progress in the use of minimal self-assembling peptides and functionalized amino acids to create hydrogels, with a focus on the challenges of understanding the structure and function of these materials and on the outlook for theUse of these modular and dynamic materials as robust networks for tissue engineering.
Journal ArticleDOI

Anisotropic and self-healing hydrogels with multi-responsive actuating capability.

TL;DR: A general in situ polymerization strategy for the fabrication of anisotropic hydrogels composed of highly-ordered lamellar network crosslinked by the metal nanostructure assemblies accompanied with remarkably anisotrop performances on mechanical, optical, de-swelling and swelling behaviors is described.
Journal ArticleDOI

Gellan gum-based hydrogels for intervertebral disc tissue-engineering applications.

TL;DR: It is observed that the produced GG–MA hydrogels possess improved mechanical properties and lower water uptake ability and degradation rate as compared to gellan gum, and are non‐cytotoxic in vitro, thus being promising biomaterials to be used in IVD tissue‐engineering strategies.
Journal ArticleDOI

Commercial hydrogels for biomedical applications.

TL;DR: This paper focuses on the commercially available hydrogels used for biomedical applications like wound dressings, contact lenses, cosmetic applications, tissue engineering, and drug delivery.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
Journal ArticleDOI

Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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