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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Modeling the tumor extracellular matrix: Tissue engineering tools repurposed towards new frontiers in cancer biology.

TL;DR: The pathological changes in tumor ECM, the limitations of 2D culture on both traditional and polyacrylamide hydrogel surfaces in modeling these characteristics and advances in both naturally derived and synthetic scaffolds to facilitate more complex and controllable 3D cancer cell culture are discussed.
Journal ArticleDOI

pH Responsive micelle self-assembled from a new amphiphilic peptide as anti-tumor drug carrier

TL;DR: The amphiphilic peptide reported in this work may be promising in clinical application for targeted drug delivery because of the low cytotoxicity and self-assembly of this peptide against both HeLa and COS7 cells.
Journal ArticleDOI

Inhomogeneous large deformation study of temperature-sensitive hydrogel

TL;DR: In this article, an explicit form of energy for temperature-sensitive hydrogel in a three-dimensional finite element method (FEM) using a user-supply subroutine in ABAQUS is presented.
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Loops versus Branch Functionality in Model Click Hydrogels

TL;DR: Strategies for counting primary loops in tetrafunctional (A2 + B4) networks and networks with mixed tri- and tetra functional (A 2 + B3/B4) junctions are reported.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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