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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye.

TL;DR: Thermoresponsive hydrogels appear to be a promising, minimally invasive platform for extended drug delivery to the posterior segment and current formulation of the gel will be modified to extend the release time and to be made fully biodegradable.
Journal ArticleDOI

Hydroxyapatite/β-tricalcium phosphate/agarose macroporous scaffolds for bone tissue engineering

TL;DR: Designed porous architecture scaffolds have been prepared with an innovative combination of techniques, avoiding the sintering stage for tissue engineering application as discussed by the authors, and they show flexibility and capacity to exert pressure into the bone defect of the patient and be easily handled by the surgeon.
Journal ArticleDOI

Integration of layered chondrocyte-seeded alginate hydrogel scaffolds.

TL;DR: The findings demonstrate the feasibility of creating stratified engineered tissues through layering and that collagen deposition is necessary for interfacial integrity and that relational properties showed almost no dependence on GAG content.
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Catechol-Functionalized Hyaluronic Acid Hydrogels Enhance Angiogenesis and Osteogenesis of Human Adipose-Derived Stem Cells in Critical Tissue Defects.

TL;DR: The feasibility of using bioinspired HA-CA hydrogels as functional biomaterials for improved tissue regeneration in critical tissue defects is proved.
References
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Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
Journal ArticleDOI

Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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