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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Controlling the adhesion and differentiation of mesenchymal stem cells using hyaluronic acid-based, doubly crosslinked networks.
TL;DR: Overall, the HA-gHGP composite matrix has great promise for directing the osteogenic differentiation of MSCs by providing an adaptable environment through the spatial presentation of cell-adhesive modules.
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3D-Printed Scaffolds and Biomaterials: Review of Alveolar Bone Augmentation and Periodontal Regeneration Applications.
Farah Asa'ad,Giorgio Pagni,Sophia P. Pilipchuk,Aldo Bruno Giannì,William V. Giannobile,Giulio Rasperini +5 more
TL;DR: Different biomaterials suitable for 3D scaffold fabrication are highlighted, with a focus on “3D-printed” ones as bone graft substitutes that might be convenient for various applications related to implant therapy.
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Collagen type I hydrogel allows migration, proliferation, and osteogenic differentiation of rat bone marrow stromal cells
Eric Hesse,Theresa E. Hefferan,James E. Tarara,Carl Haasper,Rupert Meller,Christian Krettek,Lichun Lu,Michael J. Yaszemski +7 more
TL;DR: RBMSCs started to differentiate into osteoblasts as determined by an increase in alkaline phosphatase activity after two weeks in culture, suggesting that collagen type I hydrogels could be useful for musculoskeletal regenerative therapies.
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Supramolecular hydrogels made of basic biological building blocks.
Xuewen Du,Jie Zhou,Bing Xu +2 more
TL;DR: This Focus Review describes recent advances in the use of basic biological building blocks for creating molecules that act as hydrogelators and the potential applications of the corresponding hydrogels and offers a perspective and outlook on this fast-growing field at the interface of organic chemistry, materials, biology, and medicine.
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A Multiscale Model for Solute Diffusion in Hydrogels
Eneko Axpe,Eneko Axpe,Doreen Chan,Giovanni S. Offeddu,Yin Chang,David Merida,Hector Lopez Hernandez,Eric A. Appel +7 more
TL;DR: The model presented outperforms traditional models in predicting solute diffusivity in hydrogel and provides a practical approach to predicting the transport properties of solutes such as drugs through hydrogels used in many biomedical applications.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.