Journal ArticleDOI
Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Facile in-situ fabrication of novel organic nanoparticle hydrogels with excellent mechanical properties
TL;DR: In this article, a kind of well-defined organic nanoparticle composite polyacrylamide (PAAm) hydrogels (OC gels) are successfully fabricated using in-situ free-radical polymerization with polystyrene (PS) nanoparticles as the cross-linker.
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Room-temperature self-healing tough nanocomposite hydrogel crosslinked by zirconium hydroxide nanoparticles
TL;DR: In this article, the authors demonstrate a design of novel zirconium hydroxide crosslinking nanocomposite hydrogel that combine high toughness (compressive strength of 36.6 MPa and tensile strength of 404.3 KPa) and self-healing efficiency (86%) at ambient condition.
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Ischemic heart diseases: Current treatments and future
TL;DR: The current status and future of the treatment of ischemic heart diseases with conventional medical therapy, biopharmaceutical-based therapy focused on the proteins and polymeric hydrogels for delivery of therapeutic proteins are explored.
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Reactive macromolecular micelle crosslinked highly elastic hydrogel with water-triggered shape-memory behaviour
TL;DR: A novel, highly elastic polyacrylamide-based hydrogel was developed based on the micellar copolymerization technique using a polymerizable macromolecular micelle with hydrophobic cores locked by hydrogen bonds as a multifunctional crosslinker that showed highly stretchable behaviour and even better resilience than the as-prepared hydrogels.
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Non-fouling Hydrogels of 2-Hydroxyethyl Methacrylate and Zwitterionic Carboxybetaine (Meth)acrylamides
TL;DR: By increasing the content of the zwitterionic comonomer, a 4-fold increase in the water content could be achieved while retaining mechanical properties close to the widely used poly(HEMA) hydrogels.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.