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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Engineered adipose tissue from human mesenchymal stem cells maintains predefined shape and dimension: implications in soft tissue augmentation and reconstruction.
TL;DR: It is demonstrated that adipose tissue engineered from human mesenchymal stem cells can retain predefined shape and dimensions for soft tissue augmentation and reconstruction.
Journal ArticleDOI
Cryogels for biomedical applications
Timothy M A Henderson,Katharina Ladewig,David N. Haylock,David N. Haylock,Keith M. McLean,Andrea J. O'Connor +5 more
TL;DR: This review highlights recent advances in cryogelation techniques and starting materials that can be utilised to synthesise biocompatible and biologically relevant cryogels as well as discussing physicochemical characterisation techniques for these materials.
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Synthesis and characterization of new injectable and degradable dextran-based hydrogels
TL;DR: In this paper, injectable and degradable dextran-based hydrogels were prepared without the use of initiators, and they were crosslinked with adipic acid dihydrazide (AAD), forming a gel within 2-4min.
Journal ArticleDOI
Microfluidic models of vascular functions.
TL;DR: The advantages of microfluidics are highlighted in four areas: the investigation of hemodynamics on a capillary length scale, the modulation of fluid streams over vascular cells, angiogenesis induced by the exposure of vascular cells to well-defined gradients in growth factors or pressure, and the growth of microvascular networks in biomaterials.
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Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds.
TL;DR: Recent endeavors of exploiting bioorthogonal click chemistry toward the development of poly(ethylene glycol) hydrogels as cell culture scaffolds as well as biocompatible materials are emphasized.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.