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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Macromolecule and Particle Dynamics in Confined Media

TL;DR: In this article, the authors introduce the effect of particle size, shape, surface modification, and enthalpic interactions on polymer diffusion and further relate dynamic studies in PNCs to macromolecular transport in bio-related systems and nanopores.
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Synthesis and characterization of arginine-NIPAAm hybrid hydrogel as wound dressing: In vitro and in vivo study.

TL;DR: The results showed the nontoxicity and antimicrobial P(M-Arg/NIPAAm) hydrogel accelerated the full-thickness wound healing process and had the potential application in wound dressing.
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The construction of 3D-engineered tissues composed of cells and extracellular matrices by hydrogel template approach.

TL;DR: 3D-engineered tissues constructed by the hydrogel template approach may be useful as a new class of soft-tissue engineering technology to substitute a synthetic polymer scaffold to the ECM scaffold produced from the cultured cells.
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Laponite nanoparticle-associated silated hydroxypropylmethyl cellulose as an injectable reinforced interpenetrating network hydrogel for cartilage tissue engineering

TL;DR: A new hybrid construct demonstrates an interpenetrating network (IPN) which enhances the hydrogel mechanical properties without interfering with its cytocompatibility, O2 diffusion and the ability of chondrogenic cells to self-organize in cluster and produce extracellular matrix components.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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