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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Poly(N-isopropylacrylamide) (PNIPAM)-grafted gelatin hydrogel surfaces: interrelationship between microscopic structure and mechanical property of surface regions and cell adhesiveness
TL;DR: The results confirmed that human umbilical vein endothelial cells adhered and spread on PNIPAM-gelatin hydrogels with the highest P/G, whereas reduced adhesion and nonspreading, round-shaped cells resided on the hydrogel with lower P/Gs.
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Biocompatibility of injectable chitosan–phospholipid implant systems
TL;DR: The biocompatibility of PoLi(gel)-LA is established and its potential for use in various localized therapeutic applications is indicated, although greater cell viability was seen with Po Li(gel-LA.
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A “click-chemistry” approach to cellulose-based hydrogels
TL;DR: In this article, a multi-step cellulose derivatives bearing azide-and alkyne moieties were prepared by conversion of cellulose p -toluenesulphonic acid ester with sodium azide, on one hand, and propargylamine, on the other.
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Conducting bio-materials based on gellan gum hydrogels
TL;DR: The biocompatibility of gellan gum hydrogels is demonstrated and it is shown that cell behaviour is influenced by gel modulus and the incorporation of surface topographical features.
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Encapsulation of adipose-derived stem cells and transforming growth factor-β1 in carrageenan-based hydrogels for cartilage tissue engineering:
TL;DR: Findings indicate that this new system for cartilage TE is very promising for injectable thermoresponsive formulation applications.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.