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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
About
This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Exceptionally small supramolecular hydrogelators based on aromatic–aromatic interactions

TL;DR: The use of an aromatic–aromatic interaction is reported to produce small molecule hydrogelators that self-assemble in water and form molecular nanofibers in the resulting hydrogels.
Journal ArticleDOI

Peptide Hydrogel as an Intraocular Drug Delivery System for Inhibition of Postoperative Scarring Formation

TL;DR: The pathology and immunohistochemistry demonstrate that the filtration fistula is patent without postoperative scarring formation, resulting in the significantly low intraocular pressure (IOP) of the rabbit eyes within postoperative 28 days.
Journal ArticleDOI

Dynamic Hydrogels from Host-Guest Supramolecular Interactions.

TL;DR: Host-guest supramolecular hydrogels lend themselves to a variety of applications resulting from their dynamic properties that arise from non-covalent supramolescular interactions, as well as engineered responsiveness to external stimuli, an exciting new class of materials.
Journal ArticleDOI

A Thermogelling Supramolecular Hydrogel with Sponge-Like Morphology as a Cytocompatible Bioink

TL;DR: A novel thermogelling block copolymer is synthesized and the rheological properties of its aqueous solution are investigated by viscosimetry and rheology, and excellent cytocompatibility was demonstrated with NIH 3T3 fibroblasts.
Journal ArticleDOI

Cultivation of endothelial cells on adhesive protein-free synthetic polymer gels.

TL;DR: It was found that hydrogels with a negative zeta potential higher than about 20 mV facilitates cell proliferation, and bovine fetal aorta endothelial cells can adhere, spread, proliferate, and reach confluence on poly(acrylic acid), poly(sodium p-styrene sulfonate), and poly(2-acrylamido-2- methyl-1-propanesulfonic sodium) gels.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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