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Journal ArticleDOI

Hydrogels for tissue engineering.

Kuen Yong Lee, +1 more
- 31 May 2001 - 
- Vol. 101, Iss: 7, pp 1869-1879
About
This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Book ChapterDOI

Injectable synthetic extracellular matrices for tissue engineering and repair.

TL;DR: This work focuses on hydrogels based on the extracellular matrix, a heterogeneous collection of covalent and noncovalent molecular interactions comprised primary of proteins and glycosaminoglycans (GAGs)6.
Journal ArticleDOI

Biofabrication Under Fluorocarbon: A Novel Freeform Fabrication Technique to Generate High Aspect Ratio Tissue-Engineered Constructs

TL;DR: Submerged bioprinting seems particularly suited to fabricate hollow structures with a high aspect ratio like vascular grafts for cardiovascular tissue engineering as well as branching or cantilever-like structures, obviating the need for a solid support beneath the overhanging protrusions.
Journal ArticleDOI

Programmed DNAzyme-Triggered Dissolution of DNA-Based Hydrogels: Means for Controlled Release of Biocatalysts and for the Activation of Enzyme Cascades

TL;DR: Three different hydrogels are prepared by the cross-linking of the acrylamide-DNA chains with metal ion-dependent DNAzyme sequences and their substrates, resulting in the activation of the β-Gal/GOx or GOx/HRP bienzyme cascades and of theβ-Gal-GOx-HRP trienzyme cascade.
Journal ArticleDOI

Effect of the crosslinking level on the properties of temperature‐sensitive poly(N‐isopropylacrylamide) hydrogels

TL;DR: In this article, the effect of the level of crosslinking on the properties of poly(N-isopropylacrylamide) (PNIPAAm) hydrogels was investigated in terms of their lower critical solution temperature (LCST), interior morphology, equilibrium swelling, and deswelling and swelling kinetics.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Solution Properties of Poly(N-isopropylacrylamide)

TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
Journal ArticleDOI

Polymeric Systems for Controlled Drug Release

TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI

Alginate hydrogels as synthetic extracellular matrix materials

TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
Journal ArticleDOI

Biodegradable block copolymers as injectable drug-delivery systems

TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.
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