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Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Crosslinked compounds and methods of making and using thereof
TL;DR: In this paper, methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds or (2) by the reaction between at least one tbiol compound with at least 1 thiol-reactive compound are described.
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Superior hybrid hydrogels of polyacrylamide enhanced by bacterial cellulose nanofiber clusters
TL;DR: The cell viability results suggested that PAM/BC hybrid hydrogel was benign for biomedical application and offer a great promise as biomaterials such as bone and cartilage repair materials.
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Preparation and characterization of chitosan/polyguluronate nanoparticles for siRNA delivery.
TL;DR: Chitosan/PG nanoparticles were considered promising for siRNA delivery due to their low cytotoxicity and ability to transport siRNA into cells, which can effectively inhibit induction of targeting mRNA.
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Cross-linking of dialdehyde carboxymethyl cellulose with silk sericin to reinforce sericin film for potential biomedical application.
TL;DR: A novel strategy of cross-linking of sericin with DCMC via the Schiff's base reaction is developed, which demonstrated the DCMC/SS film had excellent blood compatibility, cytocompatibility and promoting cell proliferation activity by the hemolysis ratio analysis, cell adhesion, cells viability and proliferation assays.
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Direct Observation of Early-Time Hydrogelation in β-Hairpin Peptide Self-Assembly
TL;DR: In this article, the authors show that dangling fibrils extend from one growing cluster to another and lead to early, intercluster communication in solution, and that finite interpenetration of percolating clusters with smaller clusters, along with permanent inter-cluster entanglements, increase the network rigidity.
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.