Journal ArticleDOI
Hydrogels for tissue engineering.
Kuen Yong Lee,David J. Mooney +1 more
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This article is published in Chemical Reviews.The article was published on 2001-05-31. It has received 4511 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Cellulose-based hydrogel materials: chemistry, properties and their prospective applications
TL;DR: An overview of the recent and contemporary research regarding physiochemical properties of cellulose-based hydrogels along with their applications in multidisciplinary areas including biomedical fields such as drug delivery, tissue engineering and wound healing, healthcare and hygienic products as well as in agriculture, textiles and industrial applications as smart materials.
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An improved hydrophilicity via electrospinning for enhanced cell attachment and proliferation.
TL;DR: The in vitro cell attachment on the hydrophobic PCL and hydrophilically modified PCL/PVA mats was compared by culture studies using human prostate epithelial cells (HPECs) and the attachment and proliferation rate of HPECs were improved by introducing PVA into the electrospun PCL mats.
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High-Strength, Tough, and Self-Healing Nanocomposite Physical Hydrogels Based on the Synergistic Effects of Dynamic Hydrogen Bond and Dual Coordination Bonds
TL;DR: A simple one-pot strategy to prepare a fully physically cross-linked nanocomposite hydrogel through the formation of the hydrogen bonds and dual metal-carboxylate coordination bonds within supramolecular networks, in which iron ions and TEMPO oxidized cellulose nanofibrils (CNFs) acted as cross-linkers and led to the improved mechanical strength, toughness, time-dependent self-recovery capability and self-healing property.
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Modification of collagen with a natural cross-linker, procyanidin.
TL;DR: Procyanidin stabilizes collagen as a cross-linker and preserves its triple helical structure under acidic conditions, and differential scanning calorimetry and thermogravimetric measurements reveal that the collagen/procyanodin films have improved thermal stability in comparison with pure collagen.
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Photopolymerization of cell-encapsulating hydrogels: crosslinking efficiency versus cytotoxicity.
TL;DR: Cytocompatibility may be compromised by unnecessarily prolonging exposure to cytotoxic free radicals or inadvertently enhancing the instantaneous dose of radicals in solution, both of which are dependent on the PI type/concentration and irradiation intensity.
References
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Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
TL;DR: In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Alginate hydrogels as synthetic extracellular matrix materials
TL;DR: Alginate may prove to be an ideal material with which to confer specific cellular interactive properties, potentially allowing for the control of long-term gene expression of cells within these matrices.
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Biodegradable block copolymers as injectable drug-delivery systems
TL;DR: The synthesis of a thermosensitive, biodegradable hydrogel consisting of blocks of poly(ethylene oxide) and poly(L-lactic acid) and aqueous solutions of these copolymers exhibit temperature-dependent reversible gel–sol transitions.