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Allan Linneberg
Researcher at University of Copenhagen
Publications - 623
Citations - 58621
Allan Linneberg is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 85, co-authored 577 publications receiving 45508 citations. Previous affiliations of Allan Linneberg include Copenhagen University Hospital & Glostrup Hospital.
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Journal ArticleDOI
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Paul Nioi,Asgeir Sigurdsson,Gudmar Thorleifsson,Hannes Helgason,Arna B Agustsdottir,Gudmundur L. Norddahl,Anna Helgadottir,Audur Magnusdottir,Aslaug Jonasdottir,Solveig Gretarsdottir,Ingileif Jonsdottir,Valgerdur Steinthorsdottir,Thorunn Rafnar,Dorine W. Swinkels,Tessel E. Galesloot,Niels Grarup,Torben Jørgensen,Henrik Vestergaard,Torben Hansen,Torsten Lauritzen,Allan Linneberg,Nele Friedrich,Nikolaj T. Krarup,Mogens Fenger,Ulrik Abildgaard,Peter Riis Hansen,Anders Galløe,Anders Galløe,Peter S. Braund,Christopher P. Nelson,Alistair S. Hall,Michael J.A. Williams,Andre M. van Rij,Gregory T. Jones,Riyaz S. Patel,Allan I Levey,Salim S. Hayek,Svati H. Shah,Muredach P. Reilly,Gudmundur I. Eyjolfsson,Olof Sigurdardottir,Isleifur Olafsson,Lambertus A. Kiemeney,Arshed A. Quyyumi,Daniel J. Rader,William E. Kraus,Nilesh J. Samani,Oluf Pedersen,Gudmundur Thorgeirsson,Gisli Masson,Hilma Holm,Daniel F. Gudbjartsson,Patrick Sulem,Unnur Thorsteinsdottir,Kari Stefansson +54 more
TL;DR: ASGR1 haploinsufficiency was associated with reduced levels of non-HDL cholesterol and a reduced risk of coronary artery disease, and a rare noncoding 12-base-pair deletion in intron 4 of ASGR1 was found.
Journal ArticleDOI
A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes
Natalie R. van Zuydam,Emma Ahlqvist,Niina Sandholm,Harshal Deshmukh,N. William Rayner,N. William Rayner,Moustafa Abdalla,Claes Ladenvall,Daniel Ziemek,Eric B. Fauman,Neil R. Robertson,Paul M. McKeigue,Erkka Valo,Carol Forsblom,Valma Harjutsalo,Finnish Diabetic Nephropathy Study,Annalisa Perna,Erica Rurali,M. Loredana Marcovecchio,Robert P. Igo,Rany M. Salem,Norberto Perico,Maria Lajer,Annemari Käräjämäki,M Imamura,Michiaki Kubo,Atsushi Takahashi,Xueling Sim,Jianjun Liu,Jianjun Liu,Rob M. van Dam,Guozhi Jiang,Claudia H. T. Tam,Andrea O.Y. Luk,Heung Man Lee,Cadmon K.P. Lim,Cheuk-Chun Szeto,Wing-Yee So,Juliana C.N. Chan,Su Fen Ang,Rajkumar Dorajoo,Ling Wang,Tan Si Hua Clara,Amy Jayne McKnight,Seamus Duffy,Warren,Marcus G. Pezzolesi,Michel Marre,Beata Gyorgy,Samy Hadjadj,Linda T. Hiraki,Diabetes Control,Diabetes Control,Complications Trial,Tarunveer S. Ahluwalia,Peter Almgren,Christina-Alexandra Schulz,Marju Orho-Melander,Allan Linneberg,Cramer Christensen,Daniel R. Witte,Niels Grarup,Ivan Brandslund,Olle Melander,Olle Melander,Olle Melander,Andrew D. Paterson,David A. Tregouet,Alexander P. Maxwell,Su Chi Lim,Su Chi Lim,Ronald C.W. Ma,E. Shyong Tai,Shiro Maeda,Valeriya Lyssenko,Valeriya Lyssenko,Valeriya Lyssenko,Tiinamaija Tuomi,Tiinamaija Tuomi,Andrzej S. Krolewski,Stephen S. Rich,Joel N. Hirschhorn,Joel N. Hirschhorn,Jose C. Florez,Jose C. Florez,David B. Dunger,David B. Dunger,Oluf Pedersen,Torben Hansen,Peter Rossing,Giuseppe Remuzzi,Surrogate Markers for Micro,Mary Julia Brosnan,Mary Julia Brosnan,Colin N. A. Palmer,Per-Henrik Groop,Per-Henrik Groop,Helen M. Colhoun,Leif Groop,Leif Groop,Mark I. McCarthy +100 more
TL;DR: The authors conducted a genome-wide association study (GWAS) of diabetic kidney disease in type 2 diabetes (T2D) using eight complementary dichotomous and quantitative kidney disease phenotypes.
Journal ArticleDOI
Genetic Architecture of Vitamin B 12 and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets
Niels Grarup,Patrick Sulem,Camilla H. Sandholt,Gudmar Thorleifsson,Tarunveer S. Ahluwalia,Valgerdur Steinthorsdottir,Helgi Bjarnason,Daniel F. Gudbjartsson,Olafur T. Magnusson,Thomas Sparsø,Anders Albrechtsen,Augustine Kong,Gisli Masson,Geng Tian,Hongzhi Cao,Chao Nie,Karsten Kristiansen,Lise Lotte N. Husemoen,Betina H. Thuesen,Yingrui Li,Rasmus Nielsen,Rasmus Nielsen,Allan Linneberg,Isleifur Olafsson,Gudmundur I. Eyjolfsson,Torben Jørgensen,Torben Jørgensen,Torben Jørgensen,Jun Wang,Torben Hansen,Torben Hansen,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Oluf Pedersen +35 more
TL;DR: Large Icelandic whole genome sequence dataset combined with Danish exome sequence data is used to gain insight into the genetic architecture of serum levels of vitamin B12 (B12) and folate and demonstrates the value of combining whole genome and exome sequencing approaches to ascertain the genetic and molecular architectures underlying quantitative trait associations.
Posted ContentDOI
Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Anubha Mahajan,Cassandra N. Spracklen,Weihua Zhang,Maggie C.Y. Ng,Lauren E. Petty,Kitajima H,Yu Gz,S. Rüeger,Leo Speidel,Young-Jin Kim,Momoko Horikoshi,Josep M. Mercader,Daniel Taliun,Sanghoon Moon,Soo Heon Kwak,Neil R. Robertson,Nigel W. Rayner,Loh M,Bong-Jo Kim,Joshua Chiou,Irene Miguel-Escalada,Briotta Parolo Pd,Kuang Lin,Fiona Bragg,Preuss Mh,Fumihiko Takeuchi,Jana Nano,Xiuqing Guo,Lamri A,Masahiro Nakatochi,Robert A. Scott,Jin-Moo Lee,Alicia Huerta-Chagoya,Misa Graff,Jin-Fang Chai,Esteban J. Parra,Jie Yao,L.F. Bielak,Yasuharu Tabara,Yang Hai,Steinthorsdottir,James P. Cook,Mart Kals,Niels Grarup,Ellen M. Schmidt,Pan I,Tamar Sofer,Matthias Wuttke,Chloé Sarnowski,C Gieger,Darryl Nousome,Stella Trompet,Jirong Long,Sun M,Tong L,Wei Chen,Ahmad M,Raymond Noordam,Lim Vj,Claudia H. T. Tam,Yoonjung Yoonie Joo,Chao-Jung Chen,Laura M. Raffield,Cécile Lecoeur,Nisa M. Maruthur,Bram P. Prins,Aude Nicolas,Lisa R. Yanek,Guanjie Chen,Richard A. Jensen,Salman M. Tajuddin,Edmond K. Kabagambe,Ping An,Anny H. Xiang,Choi Hs,Brian E. Cade,Jingyi Tan,Abaitua F,Linda S. Adair,Adebowale Adeyemo,Carlos A. Aguilar-Salinas,Masato Akiyama,Sonia S. Anand,Alain G. Bertoni,Bian Z,Jette Bork-Jensen,Ivan Brandslund,Jennifer A. Brody,Chad M. Brummett,Thomas A. Buchanan,Mickaël Canouil,Juliana C.N. Chan,Li-Ching Chang,Miao-Li Chee,Chen J,Chen S,Yuan-Tsong Chen,Zhengming Chen,Lee-Ming Chuang,Mary Cushman,Swapan K Das,de Silva Hj,George Dedoussis,Latchezar Dimitrov,Ayo P. Doumatey,Shufa Du,Qing Duan,Kai-Uwe Eckardt,Leslie S. Emery,Daniel S. Evans,Michelle K. Evans,Krista Fischer,James S. Floyd,Ian Ford,Myriam Fornage,Oscar H. Franco,Timothy M. Frayling,Barry I. Freedman,Christian Fuchsberger,Pauline Genter,Hertzel C. Gerstein,Giedraitis,Clicerio González-Villalpando,María Elena González-Villalpando,Mark O. Goodarzi,Penny Gordon-Larsen,David U. Gorkin,Myron D. Gross,Yuming Guo,Sophie Hackinger,Sohee Han,Andrew T. Hattersley,C. Herder,Annie-Green Howard,Willa A. Hsueh,Huang M,Wei Huang,Yi-Jen Hung,Mi Yeong Hwang,Chii-Min Hwu,Sahoko Ichihara,Mohammad Arfan Ikram,Martin Ingelsson,Islam Mt,Motohide Isono,Jang H,Jasmine F,Jiang G,Jost B. Jonas,Marit E. Jørgensen,Torben Jørgensen,Yoichiro Kamatani,Kandeel Fr,Anuradhani Kasturiratne,Tomohiro Katsuya,Kaur,Takahisa Kawaguchi,Jacob M. Keaton,Abel N. Kho,Chiea Chuen Khor,Kibriya Mg,Donghee Kim,Kohara K,Jennifer Kriebel,Florian Kronenberg,Johanna Kuusisto,Kristi Läll,Leslie A. Lange,Lee M,Nanette R. Lee,Aaron Leong,Lin Li,Yun Li,Ruifang Li-Gao,Symen Ligthart,C M Lindgren,Allan Linneberg,Ching-Ti Liu,Jiang Liu,Adam E. Locke,Tin Louie,Jian'an Luan,Luk Ao,Luo X,Jun Lv,Lyssenko,Mamakou,K. R. Mani,Meitinger T,A. Metspalu,Andrew D. Morris,Girish N. Nadkarni,Jerry L. Nadler,Mike A. Nalls,Uma Nayak,Ioanna Ntalla,Yukinori Okada,Lorena Orozco,Patel,Mark A. Pereira,Annette Peters,Pirie Fj,Bianca Porneala,Gauri Prasad,Sebastian Preissl,Laura J. Rasmussen-Torvik,Alexander P. Reiner,Michael Roden,Rebecca Rohde,Kathryn Roll,Charumathi Sabanayagam,Maike Sander,Kevin Sandow,Naveed Sattar,Sebastian Schönherr,Claudia Schurmann,Shahriar M,Shi Jinxiu,Shin Dm,Daniel Shriner,Jennifer A. Smith,Wing-Yee So,Alena Stančáková,Adrienne M. Stilp,Konstantin Strauch,Suzuki K,Atsushi Takahashi,Kent D. Taylor,Barbara Thorand,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Brian Tomlinson,Jason M. Torres,Tsai F,J. Tuomilehto,Teresa Tusié-Luna,Miriam S. Udler,Adan Valladares-Salgado,van Dam Rm,van Klinken Jb,Varma R,Marijana Vujkovic,Niels Wacher-Rodarte,Eleanor Wheeler,Eric A. Whitsel,Anand +245 more
TL;DR: Improved fine-mapping enabled systematic assessment of candidate causal genes and molecular mechanisms through which T2D associations are mediated, laying foundations for functional investigations.
Journal ArticleDOI
The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population.
Jacob P. Thyssen,Jeanne D. Johansen,Allan Linneberg,Torkil Menné,Niels Henrik Nielsen,Michael Meldgaard,Pal B. Szecsi,Steen Stender,Berit C. Carlsen +8 more
TL;DR: It is proposed that the low degree of genetic predisposition to nickel sensitization found by a Danish twin study was explained by a high prevalence of ear piercing among participants resulting in ‘bypassing’ of the filaggrin proteins.