Carlos Bustamante

TL;DR: The power of the likelihood ratio tests (LRT) of neutrality for varying levels of mutation and selection as well as the robustness of the LRT to deviations from the assumption of free recombination among sites are explored.

TL;DR: A fine-scale genetic map is constructed from patterns of linkage disequilibrium assessed using high-throughput sequence data from 51 free-ranging dogs to show that biased gene conversion is a plausible mechanism by which the high CpG content of the dog genome could have occurred.

TL;DR: A suite of SNP-based resources have been developed and made publicly available for broad application in rice research, including large SNP datasets, tools for identifying informative SNPs for targeted applications, and a suite of custom-designed SNP assays for use in marker-assisted and genomic selection, association and QTL mapping, positional cloning, pedigree analysis, variety identification and seed purity testing as mentioned in this paper.

TL;DR: Examination of mtDNA replicative intermediates from mouse liver using atomic force microscopy and 2D agarose gel electrophoresis provides evidence for only the orthodox, strand-displacement mode of replication and reveals the presence of additional, alternative origins of lagging light-strand mtDNA synthesis.

TL;DR: A kinetic model is formulated describing how a protein can regulate its own synthesis by the force generated during folding, tuning ribosome activity to structure acquisition by a nascent polypeptide.