C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
Papers
More filters
Posted ContentDOI
High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs
John E. Gorzynski,Hannah N. De Jong,David Amar,Christopher R. Hughes,Alexander G. Ioannidis,Rob Bierman,Darren Liu,Yosuke Tanigawa,Amy Kistler,Jack Kamm,Jaehee Kim,Lorenzo Cappello,Norma Neff,Simone Rubinacci,Olivier Delaneau,Massa J. Shoura,Kinya Seo,Anna Kirillova,Archana Raja,Shirley Sutton,ChunHong Huang,Malaya K. Sahoo,Kalyan C. Mallempati,Gonzalo Montero-Martín,Kazutoyo Osoegawa,David Jimenez-Morales,Nathaniel Watson,Nathan Hammond,Ruchi Joshi,Marcelo Fernandez-Vina,Jeffrey W. Christle,Matthew T. Wheeler,Phil Febbo,Kyle Kai-How Farh,Gary P. Schroth,F Desouza,Julia A. Palacios,Julia Salzman,Benjamin A. Pinsky,Manuel A. Rivas,Carlos Bustamante,Euan A. Ashley,Victoria N. Parikh +42 more
TL;DR: A scalable, high throughput approach to generate high fidelity low pass whole genome and HLA sequencing, viral genomes, and representation of human transcriptome from single nasopharyngeal swabs of COVID19 patients is developed.
Journal ArticleDOI
A method for imaging E. coli. RNA polymerase holoenzyme with the scanning tunneling microscope in an aqueous environment
TL;DR: An electodeposition method has been developed for depositing E. coli RNA polymerase onto a monoatomically flat gold surface and time‐dependence studies were conducted to help determine the binding mechanism of the protein.
Posted ContentDOI
Human demographic history impacts genetic risk prediction across diverse populations
Alicia R. Martin,Christopher R. Gignoux,Raymond K. Walters,Genevieve L. Wojcik,Benjamin M. Neale,Simon Gravel,Mark J. Daly,Carlos Bustamante,Eimear E. Kenny +8 more
TL;DR: This work disentangle recent population history in the widely-used 1000 Genomes Project reference panel with an emphasis on populations underrepresented in medical studies, and highlights the need for generalized risk prediction methods and the inclusion of more diverse individuals in medical genomics.
Journal ArticleDOI
Coupling translocation with nucleic acid unwinding by NS3 helicase.
TL;DR: The model predicts that the NS3 helicase actively unwinds duplex by reducing more than 50% the free energy that stabilizes base pairing/stacking, which lowers the average unwinding efficiency to less than 1 bp per ATP cycle.
Posted ContentDOI
Molecular Organization of the Early Stages of Nucleosome Phase Separation Visualized by Cryo-Electron Tomography
Meng Zhang,Meng Zhang,Meng Zhang,César Díaz-Celis,César Díaz-Celis,Bibiana Onoa,Cristhian Cañari-Chumpitaz,Katherinne I. Requejo,Katherinne I. Requejo,Jianfang Liu,Michael Vien,Eva Nogales,Gang Ren,Carlos Bustamante +13 more
TL;DR: In this paper, the authors used deep learning-based 3D reconstruction/segmentation to determine the molecular organization of condensates at various stages of liquid-liquid phase separation (LLPS).