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Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
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Journal ArticleDOI
Limitations of Constant-Force-Feedback Experiments
Phillip J. Elms,Phillip J. Elms,John Chodera,Carlos Bustamante,Susan Marqusee,Susan Marqusee +5 more
TL;DR: It is demonstrated that the commonly used technique of force feedback has severe limitations when used to evaluate rapid macromolecular conformational transitions, and the causes are elucidated and a simple test is provided to identify and evaluate the magnitude of the effect.
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Mitogenomes illuminate the origin and migration patterns of the indigenous people of the Canary Islands.
Rosa Fregel,Rosa Fregel,Alejandra C. Ordóñez,Jonathan Santana-Cabrera,Vicente M. Cabrera,Javier Velasco-Vázquez,Verónica Alberto,Marco Moreno-Benítez,Teresa Delgado-Darias,Amelia Rodríguez-Rodríguez,Juan C Hernández,Jorge Pais,Rafaela González-Montelongo,José M. Lorenzo-Salazar,Carlos Flores,M. Carmen Cruz-de-Mercadal,Nuria Álvarez-Rodríguez,Beth Shapiro,Matilde Arnay,Carlos Bustamante +19 more
TL;DR: This phylogeographic analysis of Canarian ancient mitogenomes, the first of its kind, shows that some lineages are restricted to Central North Africa, while others have a wider distribution, including both West and Central North Morocco, and, in some cases, Europe and the Near East.
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Real-Time Imaging of the Reorientation Mechanisms of YOYO-Labelled DNA Molecules during 90° and 120° Pulsed Field Gel Electrophoresis
Sergio Gurrieri,Steven B. Smith,K. Sam Wells,Iain Johnson,Carlos Bustamante,Carlos Bustamante +5 more
TL;DR: The first clear observations of individual molecules of DNA during the reorientation process in 90 degrees PFGE and 120 degreesPFGE are shown and computer simulations used to reproduce the molecular mechanisms of motion as well as the DNA separation features are discussed.
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Interaction of water‐soluble porphyrins with single‐ and double‐stranded polyribonucleotides
TL;DR: CD and uv‐visible absorption studies with several tetracationic water‐soluble porphyrin derivatives show that some of these species can serve as probes to discriminate between A‐ and B‐conformational forms of single‐stranded polynucleotides.
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Trigger loop folding determines transcription rate of Escherichia coli’s RNA polymerase
TL;DR: Single molecule experiments with the WT and two TL-tip mutants of the Escherichia coli enzyme reveal that tip mutations modulate RNAP’s pause-free velocity, identifying TL conformational changes as one of two rate-determining steps in elongation.