C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
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Mechanics and structure of titin oligomers explored with atomic force microscopy.
TL;DR: A mechanical model of the sarcomere in which titin molecules with different contour lengths, corresponding to different isoforms, are held in a lattice is discussed in which variations in the ratio and contour length of the component chains may provide mechanisms for the fine-tuning of the Sarcomeric passive force response.
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Dynamic SpoIIIE assembly mediates septal membrane fission during Bacillus subtilis sporulation
Tinya C. Fleming,Jae Yen Shin,Sang-Hyuk Lee,Eric C. Becker,Kerwyn Casey Huang,Carlos Bustamante,Kit Pogliano +6 more
TL;DR: A new model for the role of SpoIIIE assembly in septal membrane fission is proposed that has strong implications for how the chromosome terminus crosses the septum, and this unstable protein transitions between disassembled and assembled oligomeric states.
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Determination of heat-shock transcription factor 2 stoichiometry at looped DNA complexes using scanning force microscopy.
TL;DR: Electron microscopy and scanning force microscopy are used to elucidate the structure of complexes formed between DNA and heat‐shock transcription factor (HSF) 2, a human heat‐ shock transcriptional activator that binds DNA as a trimer, and show that this association requires only the DNA binding and trimerization domains of HSF2.
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Methods for Human Demographic Inference Using Haplotype Patterns From Genomewide Single-Nucleotide Polymorphism Data
TL;DR: The proposed approximate-likelihood method to fit demographic models to human genomewide single-nucleotide polymorphism (SNP) data is applied to data collected by Perlegen Sciences and finds evidence for a severe population size reduction in northwestern Europe starting 32,500–47,500 years ago.
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Linker DNA accessibility in chromatin fibers of different conformations: a reevaluation
TL;DR: Leuba et al. as mentioned in this paper showed that the linker DNA can be cleaved by a small molecule methidiumpropyl-EDTA-Fe(II) at similar rates.