C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
Papers
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Journal ArticleDOI
Single-Molecule Studies of Protein Folding with Optical Tweezers.
TL;DR: The characterization of folding energy landscapes at high resolution, studies of structurally complex multidomain proteins, folding in the presence of chaperones, and the ability to investigate real-time cotranslational folding of a polypeptide are described.
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Theory of the interaction of light with large inhomogeneous molecular aggregates. I. Absorption
David Keller,Carlos Bustamante +1 more
TL;DR: In this paper, a general method to describe the spectroscopy of large, internally inhomogeneous particles is presented, which utilizes an approach similar to the one used by DeVoe in the treatment of the optical properties of polymers.
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The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis
K. T. Nishant,Wu Wei,Eugenio Mancera,Juan Lucas Argueso,Andreas Schlattl,Nicolas Delhomme,Xin Ma,Carlos Bustamante,Jan O. Korbel,Zhenglong Gu,Lars M. Steinmetz,Eric Alani +11 more
TL;DR: The results indicate that the diploid yeast nuclear genome is remarkably stable during the vegetative and meiotic cell cycles and support the hypothesis that peripheral regions of chromosomes are more dynamic than gene-rich central sections where structural rearrangements could be deleterious.
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Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method
Andres E. Leschziner,Anjanabha Saha,Jacqueline Wittmeyer,Yongli Zhang,Carlos Bustamante,Bradley R. Cairns,Eva Nogales +6 more
TL;DR: This work uses the orthogonal tilt reconstruction method, which is well suited for heterogeneous samples, to provide a reconstruction of the yeast RSC (remodel the structure of chromatin) complex, and presents a model of the RSC-nucleosome complex that rationalizes the single molecule results obtained by using optical tweezers.
Journal ArticleDOI
Darwinian Selection on a Selfing Locus
Kentaro Shimizu,Kentaro Shimizu,Jennifer M. Cork,Ana L. Caicedo,Charlotte Mays,Richard C. Moore,Kenneth M. Olsen,Stephanie M. Ruzsa,Graham Coop,Carlos Bustamante,Philip Awadalla,Michael D. Purugganan +11 more
TL;DR: Coalescent simulations indicate that ancillary morphological innovations associated with self-pollination can evolve rapidly after the inactivation of the self-incompatibility response, and suggest that the post-Pleistocene expansion of A. thaliana from glacial refugia may have been associated with this adaptive event.