Carlos Bustamante

TL;DR: Genomic analyses of DNA from modern individuals show that, about 800 years ago, pre-European contact occurred between Polynesian-individuals and Native American individuals from near present-day Colombia, while remote Pacific islands were still being settled.

TL;DR: It is found that weak overdominant selection can increase, rather than decrease, the substitution rate relative to levels of polymorphism, a nonintuitive result that has major implications for the interpretation of several popular tests of neutrality.

TL;DR: An exact forward-in-time algorithm that can efficiently simulate the evolution of a finite population under the Wright–Fisher model is presented and it is found that the recombination graph is generally a very good approximation for models with complete outcrossing, whereas, for model with self-fertilization, the approximation becomes slightly inexact for some combinations of selfing and recombination parameters.

TL;DR: In this paper, the authors characterized the effects of the trefoil-knotted protein MJ0366 from Methanocaldococcus jannaschii on the operation of the ClpXP protease from Escherichia coli.

TL;DR: Simulations show that SupportMix is not only more accurate than other popular admixture discovery tools but is the first admixture inference method that can efficiently scale for simultaneous analysis of 50-100 putative ancestral populations while being independent of prior demographic information.