C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
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XGMix: Local-Ancestry Inference With Stacked XGBoost
TL;DR: This work presents a method (XGMix) based on gradient boosted trees, which, while being accurate, is also simple to use, and fast to train, taking minutes on consumer-level laptops.
Journal ArticleDOI
Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers
Yue Liu,Rosalind L. Hunter-Anderson,Olivia Cheronet,Joan Eakin,Frank A. Camacho,Michael Pietrusewsky,Nadin Rohland,Alexander G. Ioannidis,J. Stephen Athens,Michele Toomay Douglas,Rona Ikehara-Quebral,Rebecca Bernardos,Brendan J. Culleton,Matthew Mah,Nicole Adamski,Nasreen Broomandkhoshbacht,Kimberly Callan,Ann Marie Lawson,Kirsten Mandl,Megan Michel,Jonas Oppenheimer,Kristin Stewardson,Fatma Zalzala,Kenneth B. Kidd,Judith R. Kidd,Theodore G. Schurr,Kathryn Auckland,Adrian V. S. Hill,Alexander J. Mentzer,Consuelo D. Quinto-Cortés,Kathryn J. H. Robson,Douglas J. Kennett,Nick Patterson,Carlos Bustamante,Andrés Moreno-Estrada,Matthew Spriggs,Miguel G. Vilar,Mark Lipson,Ron Pinhasi,David Reich +39 more
TL;DR: Liu et al. as discussed by the authors examined 164 ancient human remains from five different archaeological sites in remote Oceania from different prehistoric time frames, along with 112 present-day individuals from the same area.
Journal ArticleDOI
Dynamic RNA Regulation in the Brain Underlies Physiological Plasticity in a Hibernating Mammal.
Rui Fu,Austin E. Gillen,Katharine R. Grabek,Kent Riemondy,L. Elaine Epperson,Carlos Bustamante,Jay R. Hesselberth,Jay R. Hesselberth,Sandra L. Martin,Sandra L. Martin +9 more
TL;DR: In this paper, the 13-lined ground squirrel genome assembly was used to identify 6,505 hibernation-related, differentially-expressed and processed transcripts using RNA-seq data from three brain regions in animals whose physiological status was precisely defined using body temperature telemetry.
Posted ContentDOI
Genomic insights into the domestication of the chocolate tree, Theobroma cacao L
Omar E. Cornejo,Omar E. Cornejo,Muh-Ching Yee,Dominguez,Mary E. Andrews,Alexandra Sockell,Erika Strandberg,Donald Livingstone,Conrad Stack,Alberto Romero,Pathmanathan Umaharan,Stefan Royaert,Nilesh R. Tawari,Pauline Ng,Ray Schnell,W. Phillips,Keithanne Mockaitis,Carlos Bustamante,Juan Carlos Motamayor +18 more
TL;DR: It is shown for the first time that a single population underwent strong domestication approximately 3,600 years ago, the Criollo population, and that during the process of domestication, there was strong selection for genes involved in the metabolism of the colored protectants anthocyanins and the stimulant theobromine, as well as disease resistance genes.
Posted Content
Genome Sequencing Highlights Genes Under Selection and the Dynamic Early History of Dogs
Adam H. Freedman,Rena M. Schweizer,Ilan Gronau,Eunjung Han,Diego Ortega-Del Vecchyo,Pedro Silva,Marco Galaverni,Zhenxin Fan,Peter Marx,Belen Lorente-Galdos,Holly C. Beale,Oscar Ramirez,Farhad Hormozdiari,Can Alkan,Carles Vilà,Kevin Squire,Eli Geffen,Josip Kusak,Adam R. Boyko,Heidi G. Parker,Clarence Lee,Vasisht Tadigotla,Adam Siepel,Carlos Bustamante,Timothy T. Harkins,Stanley F. Nelson,Elaine A. Ostrander,Tomas Marques-Bonet,Robert K. Wayne,John Novembre +29 more
TL;DR: It is found that surprisingly, none of the extant wolf lineages from putative domestication centers are more closely related to dogs, and the sampled wolves instead form a sister monophyletic clade, suggesting a re-evaluation of past hypotheses of dog origin is necessary.