J
Jie Zheng
Researcher at University of Bristol
Publications - 127
Citations - 9389
Jie Zheng is an academic researcher from University of Bristol. The author has contributed to research in topics: Mendelian randomization & Medicine. The author has an hindex of 22, co-authored 76 publications receiving 4852 citations. Previous affiliations of Jie Zheng include Medical Research Council.
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Journal ArticleDOI
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study
Charleen D. Adams,Rebecca C Richmond,Diana L. Santos Ferreira,Wes Spiller,Vanessa Y Tan,Jie Zheng,Peter Würtz,Jenny L Donovan,Freddie C. Hamdy,David E. Neal,J. Athene Lane,George Davey Smith,Caroline L Relton,Rosalind A. Eeles,Christopher A. Haiman,Zsofia Kote-Jarai,Fredrick R. Schumacher,Ali Amin Al Olama,Sara Benlloch,Sara Benlloch,Kenneth Muir,Kenneth Muir,Sonja I. Berndt,David V. Conti,Fredrik Wiklund,Stephen J. Chanock,Susan M. Gapstur,Victoria L. Stevens,Catherine M. Tangen,Jyotsna Batra,Jyotsna Batra,Judith A. Clements,Judith A. Clements,Henrik Grönberg,Nora Pashayan,Nora Pashayan,Johanna Schleutker,Johanna Schleutker,Demetrius Albanes,Alicja Wolk,Catharine M L West,Lorelei A. Mucci,Geraldine Cancel-Tassin,Stella Koutros,Karina Dalsgaard Sørensen,Karina Dalsgaard Sørensen,Lovise Maehle,Ruth C. Travis,Robert J. Hamilton,Sue A. Ingles,Barry S. Rosenstein,Yong-Jie Lu,Graham G. Giles,Graham G. Giles,Adam S. Kibel,Ana Vega,Manolis Kogevinas,Kathryn L. Penney,Jong Y. Park,Janet L. Stanford,Janet L. Stanford,Cezary Cybulski,Børge G. Nordestgaard,Børge G. Nordestgaard,Hermann Brenner,Christiane Maier,Jeri Kim,Esther M. John,Esther M. John,Manuel R. Teixeira,Susan L. Neuhausen,Kim De Ruyck,Azad Hassan Abdul Razack,Lisa F. Newcomb,Lisa F. Newcomb,Davor Lessel,Radka Kaneva,Nawaid Usmani,Nawaid Usmani,Frank Claessens,Paul A. Townsend,Manuela Gago Dominguez,Monique J. Roobol,Florence Menegaux,Kay-Tee Khaw,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hardev Pandha,Stephen N. Thibodeau,Richard M. Martin +89 more
TL;DR: The largest study of metabolites and prostate cancer and found no evidence of causality for a subset of the prostate cancer–metabolite associations using two-sample Mendelian randomization (MR), suggesting the 14 MR-tested metabolites are unlikely to be mechanistically important in prostate cancer risk.
Posted ContentDOI
PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics
Jie Zheng,Tom G. Richardson,Louise A C Millard,Gibran Hemani,Christopher A. Raistrick,Bjarni J. Vilhjálmsson,Philip C Haycock,Tom R. Gaunt +7 more
TL;DR: PhenoSpD integrates existing methods and provides a simple and conservative way to reduce dimensionality for complex human traits using GWAS summary statistics, which is particularly valuable for post-GWAS analysis of complex molecular traits.
Journal ArticleDOI
Mendelian randomisation for nutritional psychiatry.
Rebecca Carnegie,Jie Zheng,Hannah M Sallis,Hannah J. Jones,Kaitlin H Wade,Jonathan Evans,Stan Zammit,Marcus R. Munafò,Marcus R. Munafò,Richard M. Martin +9 more
TL;DR: The use of Mendelian randomisation as a foundation for intervention development facilitates the best use of resources in an emerging discipline in which opportunities are rich, but resources are often poor.
Journal ArticleDOI
Long-term use of antibiotics and risk of type 2 diabetes in women: a prospective cohort study.
Jinqiu Yuan,Yanhong Jessika Hu,Yanhong Jessika Hu,Jie Zheng,Jean H. Kim,Tim Sumerlin,Youpeng Chen,Yulong He,Changhua Zhang,Jin-Ling Tang,Yihang Pan,Michael Moore +11 more
TL;DR: A longer duration of antibiotic use in recent years was associated with increased risk of type 2 diabetes in women, and Physicians should exercise caution when prescribing antibiotics, particularly for long-term use.
Journal ArticleDOI
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Gyda Bjornsdottir,Gudmar Thorleifsson,Patrick Sulem,Kristjan Norland,Egil Ferkingstad,Asmundur Oddsson,Florian Zink,Sigrun H. Lund,Muhammad Nawaz,G. Bragi Walters,Astros Skuladottir,Sigurjon A. Gudjonsson,G. Einarsson,Gisli H. Halldorsson,Valgerdur Bjarnadottir,Gardar Sveinbjornsson,Anna Helgadottir,Unnur Styrkarsdottir,Larus J. Gudmundsson,Thomas Hansen,Thomas Werge,Karina Banasik,Anders Troelsen,Søren Thorgaard Skou,Lise Wegner Thørner,Christian Erikstrup,Kaspar René Nielsen,Susan Mikkelsen,Steffen Andersen,Søren Brunak,Kristoffer Sølvsten Burgdorf,Henrik Hjalgrim,Gregor B.E. Jemec,Poul Jennum,Pär I. Johansson,Kasper René Nielsen,Mette Nyegaard,Mie Topholm Bruun,O. Pedersen,Khoa Manh Dinh,Erik Sørensen,Daniel F. Gudbjartsson,Unnur Þorsteinsdottir,Margit Hørup Larsen,Maria Didriksen,Susanne Gjørup Sækmose,Eleftheria Zeggini,Konstantinos Hatzikotoulas,Lorraine Southam,Arthur Gilly,Andrei Barysenka,Joyce B. J. van Meurs,Cindy G. Boer,André G. Uitterlinden,Lilja Stefansdottir,Helgi Jonsson,Thorvaldur Ingvarsson,Tõnu Esko,Reedik Mägi,Maris Teder-Laving,Shiro Ikegawa,Chikashi Terao,Hiroshi Takuwa,Ingrid Meulenbelt,Rodrigo Coutinho de Almeida,Margreet Kloppenburg,Margo Tuerlings,P. Eline Slagboom,Rob G H H Nelissen,Ana M. Valdes,Massimo Mangino,Aspasia Tsezou,Eleni Zengini,G. Alexiadis,George C. Babis,Kathryn S.E. Cheah,Tian T Wu,Dino Samartzis,Jason Pui Yin Cheung,Pak C. Sham,Peter Kraft,Jae H. Kang,Kristian Hveem,John-Anker Zwart,Almut Luetge,Anne Heidi Skogholt,Marianne Bakke Johnsen,Laurent F. Thomas,Bendik S. Winsvold,Maiken Elvestad Gabrielsen,Ming Ta Michael Lee,Yanfei Zhang,Steven A. Lietman,Manu Shivakumar,George Davey Smith,Joe Tobias,April Hartley,Tom R. Gaunt,Jie Zheng,Jeremy Mark Wilkinson,Julia Steinberg,Andrew P. Morris,Ingileif Jonsdottir,Aron H. Bjornsson,Ingvar Hakon Olafsson,Elfar Ulfarsson,Josep Blondal,Arnor Vikingsson,Sisse R. Ostrowski,Henrik Ullum,Unnur Thorsteinsdottir,Hreinn Stefansson,Thorgeir E. Thorgeirsson,Kari Stefansson +113 more
TL;DR: A genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and intervertebral disc disorder (IDD) was conducted in this paper .