Mark Gerstein

TL;DR: Comparative analysis of the expression profiles of wild type and various photoreceptor mutants demonstrated that during early seedling development cryptochromes are the major photoreceptors for blue-light control of transcription factor gene expression, whereas phytochrome A and phototropins play rather limited roles.

TL;DR: Analyzing the temporal order of binding of several key factors involved in the salt response of yeast to their target genes reveals a complex dynamic and hierarchical circuit in which specific combinations of transcription factors target distinct sets of genes at discrete times to coordinate a rapid and important biological response.

TL;DR: A homology-based pipeline that was developed previously to identify pseudogenes in other eukaryotic genomes is applied to the fruit fly, so as to derive the first complete survey of its pseudogene population.

TL;DR: TopNet, an automated web tool designed to address the challenge of comparing the topologies of sub- networks, found that soluble proteins had more interactions than membrane proteins and amongst soluble proteins, those that were highly expressed, had many polar amino acids, and had many alpha helices tended to have the most interaction partners.

TL;DR: It is indicated that processed ribosomal protein pseudogenes abound in mammalian genomes, but few of these are conserved between primates and rodents.